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Hyperglycemia associated with diabetes promotes a prothrombotic state by affecting a number of different steps in the clotting pathway. Which of the following would resul more rather than less clotting? Check all that apply. The correct answers reflect the effect of hyperglycemia on the clotting pathway! less conversion of plasminogen to plasmin abnormally low number of platelets platelets more sensitive to thromboxane A2 elevated conversion of plasminogen to plasmin platelets less sensitive to thromboxane A2 low sensitivity to NO and PGI2 increased prothrombin in the blood increased amount of fibrinogen in the blood less prothrombin in the blood abnormally high number of platelets less fibrinogen in the blood high sensitivity to NO and PGI2

Hyperglycemia associated with diabetes promotes a prothrombotic state by affecting a number of different steps in the clotting pathway. Which of the following would resul more rather than less clotting? Check all that apply. The correct answers reflect the effect of hyperglycemia on the clotting pathway! less conversion of plasminogen to plasmin abnormally low number of platelets platelets more sensitive to thromboxane A2 elevated conversion of plasminogen to plasmin platelets less sensitive to thromboxane A2 low sensitivity to NO and PGI2 increased prothrombin in the blood increased amount of fibrinogen in the blood less prothrombin in the blood abnormally high number of platelets less fibrinogen in the blood high sensitivity to NO and PGI2

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Title: Impact of Hyperglycemia on the Clotting Pathway** Hyperglycemia associated with diabetes promotes a prothrombotic state by affecting various steps in the clotting pathway. The following list explores the potential effects of hyperglycemia, highlighting which factors would lead to increased clotting rather than decreased clotting. The question seeks to identify the correct responses that reflect the influence of hyperglycemia on these processes. - less conversion of plasminogen to plasmin - abnormally low number of platelets - platelets more sensitive to thromboxane A2 - elevated conversion of plasminogen to plasmin - platelets less sensitive to thromboxane A2 - low sensitivity to NO and PGI2 - increased prothrombin in the blood - increased amount of fibrinogen in the blood - less prothrombin in the blood - abnormally high number of platelets - less fibrinogen in the blood - high sensitivity to NO and PGI2 **Analysis**: Each point in the list relates to a specific step in the clotting pathway that may be influenced by hyperglycemia. Understanding these effects is crucial for comprehending the implications of diabetes on coagulation and potential therapeutic interventions.
Transcribed Image Text:**Title: Impact of Hyperglycemia on the Clotting Pathway** Hyperglycemia associated with diabetes promotes a prothrombotic state by affecting various steps in the clotting pathway. The following list explores the potential effects of hyperglycemia, highlighting which factors would lead to increased clotting rather than decreased clotting. The question seeks to identify the correct responses that reflect the influence of hyperglycemia on these processes. - less conversion of plasminogen to plasmin - abnormally low number of platelets - platelets more sensitive to thromboxane A2 - elevated conversion of plasminogen to plasmin - platelets less sensitive to thromboxane A2 - low sensitivity to NO and PGI2 - increased prothrombin in the blood - increased amount of fibrinogen in the blood - less prothrombin in the blood - abnormally high number of platelets - less fibrinogen in the blood - high sensitivity to NO and PGI2 **Analysis**: Each point in the list relates to a specific step in the clotting pathway that may be influenced by hyperglycemia. Understanding these effects is crucial for comprehending the implications of diabetes on coagulation and potential therapeutic interventions.
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