Describe the sequence of events in physiological coagulation. 2) Explain the role of the following steps and molecules in platelet plug formation • Adhesion (vWF and / or collagen) • Activation (TxA2, ADP, Thrombin) • Secretion / degranulation (Ca+2) • Shape change (Ca+2) • Aggregation (GpIIb/IIIa and fibrinogen)
Describe the sequence of events in physiological coagulation. 2) Explain the role of the following steps and molecules in platelet plug formation • Adhesion (vWF and / or collagen) • Activation (TxA2, ADP, Thrombin) • Secretion / degranulation (Ca+2) • Shape change (Ca+2) • Aggregation (GpIIb/IIIa and fibrinogen)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Describe the sequence of events in physiological coagulation.
2) Explain the role of the following steps and molecules in platelet plug formation
• Adhesion (vWF and / or collagen)
• Activation (TxA2, ADP, Thrombin)
• Secretion / degranulation (Ca+2)
• Shape change (Ca+2)
• Aggregation (GpIIb/IIIa and fibrinogen)
Expert Solution
Step 1 Introduction
Coagulation is a series of processes resulting in the cessation of bleeding at a wound or injury.
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