Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface: gp120 RNA- Core with protein coat Envelope (a) Structure of HIV -Reverse transcriptase enzyme -Capsomeres of protein coat Copyright © 2001 Benjamin Cummings, an imprint of Addison Wesley Longman, Inc. T cell CD4 receptor -CXCR4 coreceptor наконода DNA (b) HIV infecting a T cell with CD4 receptors, and CXCR4 coreceptors which are distributed over the surface of the cell A. As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface of the T-helper cell. What will be the next event in the virus life cycle? B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the other common mechanism of transmission?
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syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface:
gp120
RNA-
Core with
protein coat
Envelope
(a) Structure of HIV
Copyright © 2001 Benjamin Cummings, an imprint of Addison Wesley Longman, Inc.
Edit View Insert Format Tools Table
12pt
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-Reverse
transcriptase
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A. As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction
between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface
of the T-helper cell. What will be the next event in the virus life cycle?
B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the
other common mechanism of transmission?
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