Here in Chapter 23, we learned that aniline becomes highly deactivated in the presence of a strong Lewis acid, due to coordination of the N atom to the Lewis acid. Thus, as shown below at the left, Friedel-Crafts reactions involving aniline are unfeasible. As shown in the reaction below at the right, though, this does not appear to be a problem with the N atom in pyrrole. Explain why. NH2 `CI CI No reaction Lewis acid Lewis acid catalyst catalyst
Here in Chapter 23, we learned that aniline becomes highly deactivated in the presence of a strong Lewis acid, due to coordination of the N atom to the Lewis acid. Thus, as shown below at the left, Friedel-Crafts reactions involving aniline are unfeasible. As shown in the reaction below at the right, though, this does not appear to be a problem with the N atom in pyrrole. Explain why. NH2 `CI CI No reaction Lewis acid Lewis acid catalyst catalyst
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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