hen travelling high altitude, one of the problem is alkalosis of the blood.  Remember the equation for acid balance: CO2 + H2O ⇌ H2CO3 ⇌ HCO3− + H+ If there is a low amount of CO2 outside, then greater CO2 than normal will diffuse out of the lungs. This will cause the blood to become more bas

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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When travelling high altitude, one of the problem is alkalosis of the blood. 
Remember the equation for acid balance: CO2 + H2O ⇌ H2CO3 ⇌ HCO3− + H+
If there is a low amount of CO2 outside, then greater CO2 than normal will diffuse out of the lungs. This will cause the blood to become more basic.
 
To counteract the problem, a drug may be taken to both lower the blood pressure and help correct the pH. To do this, it blocks a symporter of HCO3- and Na+ in the proximal tubule of the kidney.
 
Q: How would blocking transport of HCO3- help to lower the pH of the blood? 
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