Hb % Saturation pH 7.4 pH 7.2 KI Tissue 80 20 Hb Saturation Curve 0 Lungs 0 10 20 30 40 50 50 70 80 90 100 110 120 130 Partal Pressure (oxygen) a. Partial pressure is a way to measure the concentration of oxygen. The two arrows show the concentration of oxygen in the tissues and in the lungs. Why do you think the percent oxygen is high in the lungs and low in the tissues (1 sentence)? b. Hb % saturation is the percent of hemoglobin molecules that have bound oxygen. At 100% saturation, all of the oxygen-binding sites of hemoglobin are bound. The graphs shows two lines depicting how saturated hemoglobin would be at the different oxygen concentrations in an environment of pH7.2 (lower line) and 7.4 (upper line). Is hemoglobin in the tissues (i.e. 40 pp oxygen) more likely to be saturated at 7.2 or 7.4 (circle one)? c. In 1-2 sentences, summarize what the two lines in the graph tell you about hemoglobin's response to changes in pH. 5. Delivering oxygen to your tissues is a pretty important iob. Since pH afects that ioh it is easy

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**Hb Saturation Curve**

The graph illustrates the Hemoglobin (Hb) Saturation Curve. The horizontal axis represents the Partial Pressure of oxygen, while the vertical axis shows Hb % Saturation. There are two curves, one for pH 7.4 (red line) and the other for pH 7.2 (green line). 

- The red curve (pH 7.4) is generally higher, indicating greater saturation at each partial pressure level when compared to the green curve (pH 7.2).
- Arrows on the graph indicate that partial pressure is categorized into two regions: Tissue (left side) and Lungs (right side).

**Questions and Explanations**

a. **Partial pressure** is a way to measure the concentration of oxygen. The two arrows show the concentration of oxygen in the tissues and in the lungs. **Why do you think the percent oxygen is high in the lungs and low in the tissues (1 sentence)?**

b. **Hb % saturation** is the percent of hemoglobin molecules that have bound oxygen. At 100% saturation, all of the oxygen-binding sites of hemoglobin are bound. The graph shows two lines depicting how saturated hemoglobin would be at different oxygen concentrations in an environment of pH 7.2 (lower line) and 7.4 (upper line).

**Question**: Is hemoglobin in the tissues (i.e., 40 pp oxygen) more likely to be saturated at 7.2 or 7.4 (circle one)?

c. **Summarize what the two lines in the graph tell you about hemoglobin’s response to changes in pH (1-2 sentences).**

5. **Buffer Systems in the Body**: 
- Delivering oxygen to your tissues is crucial. pH affects this process, highlighting the importance of maintaining a stable pH. 
- Our body uses **buffers**, which contain molecules that can bind to excess protons (hydrogen ions) or hydroxide ions. 
- A typical acid-base buffer consists of a weak acid and its conjugate base (salt).
  - **Acid**: donates protons
  - **Base**: accepts protons
- Buffers work by managing the concentrations of the weak acid and its salt, ensuring large changes do not occur in response to proton or hydroxide ion additions.
- Our blood buffer system is called the **carbonic acid buffer system**.
Transcribed Image Text:**Hb Saturation Curve** The graph illustrates the Hemoglobin (Hb) Saturation Curve. The horizontal axis represents the Partial Pressure of oxygen, while the vertical axis shows Hb % Saturation. There are two curves, one for pH 7.4 (red line) and the other for pH 7.2 (green line). - The red curve (pH 7.4) is generally higher, indicating greater saturation at each partial pressure level when compared to the green curve (pH 7.2). - Arrows on the graph indicate that partial pressure is categorized into two regions: Tissue (left side) and Lungs (right side). **Questions and Explanations** a. **Partial pressure** is a way to measure the concentration of oxygen. The two arrows show the concentration of oxygen in the tissues and in the lungs. **Why do you think the percent oxygen is high in the lungs and low in the tissues (1 sentence)?** b. **Hb % saturation** is the percent of hemoglobin molecules that have bound oxygen. At 100% saturation, all of the oxygen-binding sites of hemoglobin are bound. The graph shows two lines depicting how saturated hemoglobin would be at different oxygen concentrations in an environment of pH 7.2 (lower line) and 7.4 (upper line). **Question**: Is hemoglobin in the tissues (i.e., 40 pp oxygen) more likely to be saturated at 7.2 or 7.4 (circle one)? c. **Summarize what the two lines in the graph tell you about hemoglobin’s response to changes in pH (1-2 sentences).** 5. **Buffer Systems in the Body**: - Delivering oxygen to your tissues is crucial. pH affects this process, highlighting the importance of maintaining a stable pH. - Our body uses **buffers**, which contain molecules that can bind to excess protons (hydrogen ions) or hydroxide ions. - A typical acid-base buffer consists of a weak acid and its conjugate base (salt). - **Acid**: donates protons - **Base**: accepts protons - Buffers work by managing the concentrations of the weak acid and its salt, ensuring large changes do not occur in response to proton or hydroxide ion additions. - Our blood buffer system is called the **carbonic acid buffer system**.
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