HC=0 CH, HN- N- CH2 CH2 A HN- CH, HN- CH2 CH, F IZ ŽI O IZ ZI ŽI M ZI W ŽI IZ ŽI O

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Which folate structure (from the list below)
(a) is the substrate for the enzyme that is inhibited by methotrexate and
trimethoprim?
(b) has the most highly oxidized one-carbon substituent?
(c) is used in the conversion of serine to glycine?
(d) transfers its one-carbon substituent to a B12 coenzyme? What amino acid is synthesized as the end result of this reaction?
(e) is the coenzyme for the thymidylate synthase reaction?
(f) is not known to exist in nature?
(g) is used in purine nucleotide synthesis?

HC=0
CH,
HN-
N-
CH2
CH2
A
HN-
CH, HN-
CH2
CH,
F
IZ
ŽI O
IZ
ZI
ŽI M
ZI W
ŽI
IZ
ŽI O
Transcribed Image Text:HC=0 CH, HN- N- CH2 CH2 A HN- CH, HN- CH2 CH, F IZ ŽI O IZ ZI ŽI M ZI W ŽI IZ ŽI O
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Note: Since you have posted a question with multiple subparts, we will solve the first three subparts for you. To get the remaining subparts solved, please repost the complete question and mention the subparts to be solved.

Folate or folic acid is one of the Vitamin B that is required to make red blood cells or white blood cells in the bone marrow, it also helps in the energy production from carbohydrates, also used for growth during pregnancy, adolescence.

The deficiency in the folate can cause anemia that can cause symptoms such as tiredness, lethargy, headaches, etc.

 

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