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5.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid O || H | NH,C–C−0 + H,O CH₂ CH₂ glutamic acid (Glu) NAD+ NADH + H+ ہے deaminase NH4+ + O C CH₂ T CH₂ Į_ a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid

5.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid O || H | NH,C–C−0 + H,O CH₂ CH₂ glutamic acid (Glu) NAD+ NADH + H+ ہے deaminase NH4+ + O C CH₂ T CH₂ Į_ a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed from glutamic acid, thereby producing ammonium (NH4*), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid HO NHC- CH₂ I CH₂ glutamic acid (Glu) + H₂O NAD+ NADH + H+ deaminase NH4+ + O C CH₂ CH₂ 1_0² a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid
Transcribed Image Text:15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed from glutamic acid, thereby producing ammonium (NH4*), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid HO NHC- CH₂ I CH₂ glutamic acid (Glu) + H₂O NAD+ NADH + H+ deaminase NH4+ + O C CH₂ CH₂ 1_0² a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid
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