Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Hb Zanzibar has an AspG1(94)α to Glu mutation. Which of the following statements is TRUE?
a) It has a low affinity for O2 because a hydrogen bond in the T state is broken.
b) It has a low affinity for O2 because a hydrogen bond in the R state is broken.
c) The mutant has a lower affinity for O2 due to the loss of a hydrogen bond present in the T state.
d) The Bohr effect is diminished due to the loss of the primary binding site of the Bohr proton.
e) Cooperativity in the mutant is increased because the mutation occurs in the switch region.
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