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Given the active site diagram and reaction mechanism, indicate the mechanism of irreversible inhibition for the inhibitor provided.

Given the active site diagram and reaction mechanism, indicate the mechanism of irreversible inhibition for the inhibitor provided.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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I once got non specific and another time i got uncompetitive and anothe time i got transition state analog please put the right answer

Given the active site diagram and reaction mechanism, indicate the mechanism of irreversible inhibition for the inhibitor provided. HO OH OH NH Active Site *HN NH Non-specific inhibition OH HO OOHO Uncompetitive inhibition. OH Affinity-based inhibition Transition state analog Mechanism-based inhibition Reaction Mechanism NH HN NH fint of the OH OH OH -P₁ OH HO OOH Q HO OOH OH Zn²+ Inhibitor
Transcribed Image Text:Given the active site diagram and reaction mechanism, indicate the mechanism of irreversible inhibition for the inhibitor provided. HO OH OH NH Active Site *HN NH Non-specific inhibition OH HO OOHO Uncompetitive inhibition. OH Affinity-based inhibition Transition state analog Mechanism-based inhibition Reaction Mechanism NH HN NH fint of the OH OH OH -P₁ OH HO OOH Q HO OOH OH Zn²+ Inhibitor
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