Galantamine, a natural product produced by the amaryllis family of flowering plants, has been used in the early treatment ofAlzheimer's disease. In a synthesis of galantamine and related compounds (J. Org. Chem. 2015, 80, 1952-1956), compound 1 wasconverted into compound 2. Propose an efficient synthesis for the conversion of 1 to 2A. NaOHMeOD. DMP or PCCG. HBr1MeOB. H₂SO4, H₂O, HgSO4E. Na₂Cr₂O7, H₂SO4, H₂OH. 1) O3; 2) DMSH 2xI. TsCl, pyThe conversion of 1 to 2 can be performed with some reagent or combination of the reagents listed below. Give the necessaryreagents in the correct order for each transformation, as a string of letters (without spaces or punctuation, such as "EBF"). If there ismore than one correct solution, provide just one answer.C. 1) BH3-THF; 2) H₂O2, NaOHF.HBr, ROOR=MeOIll.NMeGalanthamineOH

In the conversation from molecule 1 to molecule 2, we see that alkene has been converted to aldehyde…

Galantamine, a natural product produced by the amaryllis family of flowering plants, has been used in the early treatment of Alzheimer's disease. In a synthesis of galantamine and related compounds (J. Org. Chem. 2015, 80, 1952-1956), compound 1 was converted into compound 2. Propose an efficient synthesis for the conversion of 1 to 2 A. NaOH 380xx-360 MeO G. HBr D. DMP or PCC H MeO B. H₂SO4, H₂O, HgSO4 E. Na₂Cr₂O7, H₂SO4, H₂O H. 1) O3; 2) DMS H H 2 Meo The conversion of 1 to 2 can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order for each transformation, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. C. 1) BH3-THF; 2) H₂O2, NaOH F.HBr, ROOR I. TsCl, py Me H Galanthamine OH

Galantamine, a natural product produced by the amaryllis family of flowering plants, has been used in the early treatment of Alzheimer's disease. In a synthesis of galantamine and related compounds (J. Org. Chem. 2015, 80, 1952-1956), compound 1 was converted into compound 2. Propose an efficient synthesis for the conversion of 1 to 2 A. NaOH 380xx-360 MeO G. HBr D. DMP or PCC H MeO B. H₂SO4, H₂O, HgSO4 E. Na₂Cr₂O7, H₂SO4, H₂O H. 1) O3; 2) DMS H H 2 Meo The conversion of 1 to 2 can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order for each transformation, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. C. 1) BH3-THF; 2) H₂O2, NaOH F.HBr, ROOR I. TsCl, py Me H Galanthamine OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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