لله - od This B-diketone can be synthesized from cyclohexene and cyclopentanone using an enamine reaction; the following steps are involved: 1. Cyclohexene reacts with NBS to give allyl bromide 1; 2. Allyl bromide 1 reacts with Mg, ether to give Grignard 2; 3. Grignard 2 reacts with CO₂ then H3O+ to give acid 3; 4. Acid 3 reacts with SOC1₂ to give acid chloride 4; 5. Cyclopentanone reacts with morpholine to give enamine 5; 6. Enamine 5 reacts with acid chloride 4 to give adduct 6; 7. Adduct 6 is hydrolyzed to give the product. Draw the structure of acid 3.
لله - od This B-diketone can be synthesized from cyclohexene and cyclopentanone using an enamine reaction; the following steps are involved: 1. Cyclohexene reacts with NBS to give allyl bromide 1; 2. Allyl bromide 1 reacts with Mg, ether to give Grignard 2; 3. Grignard 2 reacts with CO₂ then H3O+ to give acid 3; 4. Acid 3 reacts with SOC1₂ to give acid chloride 4; 5. Cyclopentanone reacts with morpholine to give enamine 5; 6. Enamine 5 reacts with acid chloride 4 to give adduct 6; 7. Adduct 6 is hydrolyzed to give the product. Draw the structure of acid 3.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:لله -0.8
This B-diketone can be synthesized from cyclohexene and cyclopentanone using an enamine reaction; the following steps are involved:
1. Cyclohexene reacts with NBS to give allyl bromide 1;
2. Allyl bromide 1 reacts with Mg, ether to give Grignard 2;
3. Grignard 2 reacts with CO₂ then H3O+ to give acid 3;
4. Acid 3 reacts with SOC1₂ to give acid chloride 4;
5. Cyclopentanone reacts with morpholine to give enamine 5;
6. Enamine 5 reacts with acid chloride 4 to give adduct 6;
7. Adduct 6 is hydrolyzed to give the product.
Draw the structure of acid 3.
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