For the following synthesis scheme, fill in the missing molecules. Note, you do not understand all of this chemistry yet, but soon you will and then you will be responsible for the entire sequence of synthetic reactions! Even if you have not seen all the chemistry, please take a moment to see what kind of transformations are occuring in each step of the synthesis.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
For the following synthesis scheme, fill in the missing molecules. Note, you do not understand all of this chemistry yet, but soon you will and then you will be responsible for the entire sequence of synthetic reactions! Even if you have not seen all the chemistry, please take a moment to see what kind of transformations are occuring in each step of the synthesis.
Given
transformations of cis Alkene to trans alkene
find out all reagents
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