Find the starting materials of this compound via retrosynthetic approach (4 marks) Further synthesis the compound using any of the starting material from (a) by displaying its mechanism (6 marks) Multistep process is involved in the synthesis of an Aldol Condensation product (D). Starting with Benzene, complete the following reaction given the reaction conditions. Show by way of mechanism how A, B, C and D are derived (10 marks) i H D = . heat CI ALC13 A- NaOH, B + C A CH31 CH3

Find the starting materials of this compound via retrosynthetic approach (4 marks) Further synthesis the compound using any of the starting material from (a) by displaying its mechanism (6 marks) Multistep process is involved in the synthesis of an Aldol Condensation product (D). Starting with Benzene, complete the following reaction given the reaction conditions. Show by way of mechanism how A, B, C and D are derived (10 marks) i H D = . heat CI ALC13 A- NaOH, B + C A CH31 CH3

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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As shown below, the drug novocaine can be prepared according to the retrosynthetic sequence outlined. or H₂N O₂N Novocaine OH robin ↓↓ O₂N B CI HO E HN F (i) An FGI of novocaine leads to nitro-containing compound A. What does FGI stand for and what reagents might one choose to achieve this transformation in the forward sense (i.e. A to novocaine)? (ii) Disconnection of A leads to synthetic equivalents B and C. Show this disconnection, provide structures of the synthons, and explain how these relate to B and C. (iii) Provide a mechanism for the forward reaction, i.e. reaction of B with C to form A. (iv) Compound B can be prepared from carboxylic acid D. What reagent would you select in order to convert D into B? (v) Amino alcohol C can be prepared from epoxide E and amine F. Accordingly, show the retrosynthesis of C and then a mechanism for the forward reaction.
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