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please help Draw the mechanism for the synthesis (Include all the side products and possible enantiomers)   of the Aldol Reaction

please help Draw the mechanism for the synthesis (Include all the side products and possible enantiomers)   of the Aldol Reaction

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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please help Draw the mechanism for the synthesis (Include all the side products and possible enantiomers)   of the Aldol Reaction

 
What are the limiting reagent in the synthesis? Show your work. example: (5 grams of A)/(10 g/mol of A) = 0.5 moles of A (0.5 moles of A) (2 moles of B/1 moles of A)*(5 grams/mol of B)= 50 grams of B
Transcribed Image Text:What are the limiting reagent in the synthesis? Show your work. example: (5 grams of A)/(10 g/mol of A) = 0.5 moles of A (0.5 moles of A) (2 moles of B/1 moles of A)*(5 grams/mol of B)= 50 grams of B
The Aldol Reaction: Synthesis of Dibenzalacetone Purpose of the experiment Design and carry out an aldol condensation reaction, analyzing the yicld, purity, and structure of the product. Introduction The Aldol reaction is among the most powerful and versatile methods of carbon- carbon bond formation available to the synthetic chemist. This reaction, and its variants, have made possible the syntheses of many familiar pharmaceuticals. In this lab we will guide you to design and carry out an aldol condensation reaction between acetone and benzaldehyde to form dibenzalacetone. As part of your pre-laboratory preparation, work through the questions below. These will help you to figure out ahead of time what you will be doing in the laboratory. The general reaction for this aldol condensation can be written thus: NaO Which carbonyl compound is the nucleophile, and which is the electrophile? Draw out the mechanism for this reaction. Why is it called a mixed aldol condensation? What you will do You will aim to prepare 2 mmoles of dibenzylacetone. You first must figure out how much of acetone and benzaldehdye you will need. Do some research to fill in the table of physical constants below, then use the molecular weights and densities you found to calculate appropriate amounts of your starting materials. Physical constants for the materiais you wil use or prepare Mol. Wt. (gimol) Material density Mp ("C) Acetone Benzaldehyde NaOH Dibenzalacetone Next, write out a flow chart of directions that you will follow when carrying out this experiment. Several issues that you may wish to consider in your design are the following: Questions:
Transcribed Image Text:The Aldol Reaction: Synthesis of Dibenzalacetone Purpose of the experiment Design and carry out an aldol condensation reaction, analyzing the yicld, purity, and structure of the product. Introduction The Aldol reaction is among the most powerful and versatile methods of carbon- carbon bond formation available to the synthetic chemist. This reaction, and its variants, have made possible the syntheses of many familiar pharmaceuticals. In this lab we will guide you to design and carry out an aldol condensation reaction between acetone and benzaldehyde to form dibenzalacetone. As part of your pre-laboratory preparation, work through the questions below. These will help you to figure out ahead of time what you will be doing in the laboratory. The general reaction for this aldol condensation can be written thus: NaO Which carbonyl compound is the nucleophile, and which is the electrophile? Draw out the mechanism for this reaction. Why is it called a mixed aldol condensation? What you will do You will aim to prepare 2 mmoles of dibenzylacetone. You first must figure out how much of acetone and benzaldehdye you will need. Do some research to fill in the table of physical constants below, then use the molecular weights and densities you found to calculate appropriate amounts of your starting materials. Physical constants for the materiais you wil use or prepare Mol. Wt. (gimol) Material density Mp ("C) Acetone Benzaldehyde NaOH Dibenzalacetone Next, write out a flow chart of directions that you will follow when carrying out this experiment. Several issues that you may wish to consider in your design are the following: Questions:
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