he aldol reaction didn't stop after the initial nucleophilic attack followed by protonation of the oxygen, it continued to loss of water cross the newly formed bond. Why is this? It was favorable to lose water in order to extend the conjugation of the system. Water is always lost after an aldol reaction. It was favorable to lose water in order to increase solubility of the product. Water was not lost across the newly formed bond.

he aldol reaction didn't stop after the initial nucleophilic attack followed by protonation of the oxygen, it continued to loss of water cross the newly formed bond. Why is this? It was favorable to lose water in order to extend the conjugation of the system. Water is always lost after an aldol reaction. It was favorable to lose water in order to increase solubility of the product. Water was not lost across the newly formed bond.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter26: Aldol And Claisen Reactions

Section: Chapter Questions

Problem 54CTQ

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