Why we need step 3 before step 4? a. Because the nitro group increases the electrophilicity at the ortho positions which is where the bromine is added. b. Because the amine group is a strong ortho, para director which is what controls the regiochemical outcome of this bromination. c. Step 4 is unessesary. The symmetry of compound 3 allows for the bromination to be regioselective and give compound 5. 5. There will be a mixture of products because there is no selectivity for a major product.
Why we need step 3 before step 4? a. Because the nitro group increases the electrophilicity at the ortho positions which is where the bromine is added. b. Because the amine group is a strong ortho, para director which is what controls the regiochemical outcome of this bromination. c. Step 4 is unessesary. The symmetry of compound 3 allows for the bromination to be regioselective and give compound 5. 5. There will be a mixture of products because there is no selectivity for a major product.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Why we need step 3 before step 4?
a. Because the nitro group increases the electrophilicity at the ortho positions which is where the bromine is added.
b. Because the amine group is a strong ortho, para director which is what controls the regiochemical outcome of this bromination.
c. Step 4 is unessesary. The symmetry of compound 3 allows for the bromination to be regioselective and give compound 5.
5. There will be a mixture of products because there is no selectivity for a major product.
Transcribed Image Text:Step 3
Step 4
Br
NO2
NH2
NH2
3
4
5
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