Explain the functions of mitochondrial matrix processing peptidase (MP) and chloroplast stromal processing peptidase (SPP).

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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**Explain the functions of mitochondrial matrix processing peptidase (MP) and chloroplast stromal processing peptidase (SPP).**
Transcribed Image Text:**Explain the functions of mitochondrial matrix processing peptidase (MP) and chloroplast stromal processing peptidase (SPP).**
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Function of mitochondrial matrix processing Peptidase.

Mitochondrial processing peptidase takes care of removing the matrix-targeting pre-sequence from most precursors. This enzyme processes precursors that are fully translocated to the matrix as well as precursors in transit to the inner membrane or the intermembrane space.

Mitochondrial proteins which reach the innermost mitochondrial compartment, the Mitochondrial matrix, often undergo proteolytic cleavage of the targeting signal, performed by the Mitochondrial Processing Peptidase (MPP), this is often necessary for the maturation of the preprotein.

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