Studies on human aging have shown that the levels of coenzyme Q10 (ubiquinone), measured in tissues such as heart muscle, are significantly lower in individuals over 70 years old than in younger individuals. This lower level is associated with significantly reduced contractile force of their heart muscle. Which is the most likely explanation for the reduced heart muscle function in these older individuals? Coenzyme Q10 is an uncoupling protein found in mitochondria; lower levels of it will result in less efficient mitochondria. Coenzyme Q10 is used to convert pyruvate to acetyl CoA; lower levels of it will result in a less efficient citric acid cycle, which will slow down the production of ATP. Coenzyme Q10 is an electron carrier in the electron transport chain in mitochondria; lower levels of it will result in less ATP being made by mitochondria during cellular respiration. Coenzyme Q10 is a lipid found in brown fat; brown fat is a major source of energy for all tissues in the body. Coenzyme Q10 is used in cleaving a 6-carbon sugar into two 3-carbon sugars during glycolysis; lower levels of it will result in lower amounts of ATP being produced.
Studies on human aging have shown that the levels of coenzyme Q10 (ubiquinone), measured in tissues such as heart muscle, are significantly lower in individuals over 70 years old than in younger individuals. This lower level is associated with significantly reduced contractile force of their heart muscle. Which is the most likely explanation for the reduced heart muscle function in these older individuals? Coenzyme Q10 is an uncoupling protein found in mitochondria; lower levels of it will result in less efficient mitochondria. Coenzyme Q10 is used to convert pyruvate to acetyl CoA; lower levels of it will result in a less efficient citric acid cycle, which will slow down the production of ATP. Coenzyme Q10 is an electron carrier in the electron transport chain in mitochondria; lower levels of it will result in less ATP being made by mitochondria during cellular respiration. Coenzyme Q10 is a lipid found in brown fat; brown fat is a major source of energy for all tissues in the body. Coenzyme Q10 is used in cleaving a 6-carbon sugar into two 3-carbon sugars during glycolysis; lower levels of it will result in lower amounts of ATP being produced.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
please see attached
Transcribed Image Text:### Human Aging and Coenzyme Q10
Studies on human aging have shown that the levels of coenzyme Q10 (ubiquinone), measured in tissues such as heart muscle, are significantly lower in individuals over 70 years old than in younger individuals. This lower level is associated with significantly reduced contractile force of their heart muscle.
### Question
Which is the most likely explanation for the reduced heart muscle function in these older individuals?
- **Option A:**
Coenzyme Q10 is an uncoupling protein found in mitochondria; lower levels of it will result in less efficient mitochondria.
- **Option B:**
Coenzyme Q10 is used to convert pyruvate to acetyl CoA; lower levels of it will result in a less efficient citric acid cycle, which will slow down the production of ATP.
- **Option C:**
Coenzyme Q10 is an electron carrier in the electron transport chain in mitochondria; lower levels of it will result in less ATP being made by mitochondria during cellular respiration.
- **Option D:**
Coenzyme Q10 is a lipid found in brown fat; brown fat is a major source of energy for all tissues in the body.
- **Option E:**
Coenzyme Q10 is used in cleaving a 6-carbon sugar into two 3-carbon sugars during glycolysis; lower levels of it will result in lower amounts of ATP being produced.
This question explores the role of coenzyme Q10 in cellular energy production, emphasizing its impact on heart muscle function in older adults.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON