Q: a. What are the purposes of sequence alignment?
A: Sequence alignment is a method by which one can arrange sequences of DNA, RNA and protein so as to…
Q: Which is a limitation of using massively parallel sequencing ?
A: It is a term used to describe the method of high-throughput DNA sequencing to determine the entire…
Q: what are the purpose of sequence alignment? define local alignment and global alignment?
A: Alignments are an effective method for comparing similar DNA or protein sequences. DNA molecules are…
Q: What do you need to pay attention to when designing SNP specific primers for the detection of gene…
A: When we designing SNP specific primers for the detection of gene sequences pay attention on…
Q: Discuss theh type of information that genome-wide association studies can provide
A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…
Q: Explain Two strategies for assembling whole genome sequences.
A: All the genetic information of an organism is known as its genome. Genome assembly is defined as the…
Q: Comment on the utility of variability in number of tamndem repeats during DNA fingerprintingds?
A: Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic…
Q: Describe the technology behind identifying, synthesizing,sequencing, and amplifying DNA.
A: Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic…
Q: Describe the composition of a DNA microarray, and explain how it is used.
A: A DNA microarray is a laboratory tool which is used to detect the expression of thousands of genes…
Q: What provides a convenient bridge between the low resolution of a karyotype and the ultra-high…
A: Introduction Cytology refers to the study of cell such as cell morphology, physiology etc. As we…
Q: Explain the basic techniques used to manipulate genetic material
A: Genetic Material: A cell or an organism comprises information carrier materials found in the…
Q: Discuss the concept of the use of DNA in genome identification.
A: DNA (Deoxyribo nucleic acid) is a double stranded genetic element in all prokaryotic and eukaryotic…
Q: Why the sequence alignment is extremely important in designing a construct for developing a…
A: Sequence alignment It is defined as the way of arranging the sequences of DNA, RNA or protein to…
Q: Discuss the bioinformatics approaches that can be used to identifya protein-encoding gene.
A: The process of recognizing the protein-encoding gene is crucial and has numerous applications. Such…
Q: How to create DNA-sequence alignment ?
A: DNA-Sequence alignment can be defined as the way in which sequences of DNA samples are arranged for…
Q: Why a multiple sequence alignment is needed for researchers? What inferences can be derived from…
A: When three or more biological sequences are aligned and studied together, it is referred to as…
Q: Explain the mechanisms on the proofreading of DNA.
A: Biological macromolecules are those large molecules that are necessary for the survival and growth…
Q: How BLAST Searches Automate the Findingof Homologous Sequences?
A: Basic local alignment search tool (BLAST) is an algorithm and program for comparing primary…
Q: Explain how DNA microarrays are used in the study ofgenomics.
A: DNA (deoxyribonucleic acid) is double helix, coil structure that is responsible for transfer of…
Q: Briefly describe the steps or methods for studying genes. Start with targeting a gene region and…
A: Gel electrophoresis is a strategy for investigating DNA dependent on its size (base-pair length). As…
Q: what are similarities and differences between chain-termination and reversible terminator…
A: Gene sequencing aids in the development of gene therapy, a form of treatment that replaces faulty…
Q: Describe two methods in performing a DNA analysis, its possibleapplications, and how it can be so…
A: DNA (Deoxyribonucleic acid) analysis is a method of determining the characteristics of the…
Q: Outline different strategies for identifying gene sequences.
A: Genome is the study of all genes present in the organism. Gene is a unit of heredity that is…
Q: How to find unknown gene and design primers present using whole genome sequence?
A: Step 1 Whole genome sequencing is the process that regulates the complete deoxyribonucleic acid…
Q: How can libraries be used to locate a specific gene of interest?
A: Scientists use genetic engineering methods to create two different types of DNA libraries. These are…
Q: Explain the limitation of DNA microarrays ?
A: DNA microarray is the molecular laboratory technique that helps in studying and measuring the…
Q: How can specific genes be retrieved from a DNA library?
A: Deoxyribonucleic acid or DNA is a molecule that contains the genetic code of the organisms. DNA…
Q: Can Bioinformatics be used for sequence annotation to identifyprotein-coding and noncoding sequences…
A: The genome sequence of any organism is that organism's blueprint: the set of instructions dictating…
Q: Discuss why it is useful to search a database to identify sequencesthat are homologous to a newly…
A: The most basic operations in bioinformatics involves searching for similarities, or homologies,…
Q: describe one method for sequencing DNA and a method for determining RNA sequencing
A: It means to determine the primary structure of an unbranched biopolymer.
Q: How accurate is whole exome sequencing?
A: The goal of exome sequencing, also known as whole genome sequencing is to identify genetic variants,…
Q: "Whole-Genome Sequencing Is Widely Used for Sequencing and Assembling Entire Genomes". Explain this…
A: Whole genome sequencing It reveals an organism's complete DNA make-up ( allowing us to better…
Q: Briefly explain how a gene can be isolated through positional cloning.
A: A positional cloning is a technique used in laboratory for locating the position of a gene…
Q: Explain the advantages of DNA microarrays ?
A: A DNA microarray is a collection of microscopic DNA spots attached to a solid surface. Each DNA spot…
Q: What are the steps in extracting DNA from a Banana using simple household materials like dishwashing…
A: DNA extraction from banana is most commonly followed as banana is triploid with three sets of…
Q: Briefly explain why RNA-seq gives more information about the transcriptome than does microarray…
A: Messenger (m-RNA) ribonucleic acid is known to be transcribed from the DNA molecule, which is the…
Q: Explain the use of Annotation to Identify Gene Sequences ?
A: The attachment of biological information to the gene sequence is known as genome annotations. Three…
Q: describe techniques used to identify and quantify specific dna sequence in complex mixtures
A: Introduction Deoxyribonucleic acid (DNA) is a polymer made up of two polynucleotide chains that coil…
Q: compare oligonucleotide arrays and expression arrays
A: An oligonucleotide array is made up of a collection of short single-stranded DNA sequences…
Q: Describe several methods commonly used for the sequencing of DNA
A: DNA sequencing refers to the sequencing of the nucleotides base pairs in the genome of an organism.…
Q: List down and briefly describe three other sequence alignment tools other than BLAST used in…
A: BLAST can rapidly align and compare a query DNA sequence with a database of sequences, which makes…
Q: Describe two different types of protein microarrays, and discuss their uses.
A: Genomics and proteomics are relatively new branches of genetics. Genomics is the study of all the…
Explain how substitution matrices can be used to improve the possibility of identifying related protein sequences.
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Solved in 2 steps
- Discuss the concept of the use of DNA in genome identification.If you have access to the necessary computer software, make asequence file and analyze it in the following ways: What is thetranslated sequence in all three reading frames? What is the longest open reading frame? Is the sequence homologous to any known sequences? If so, does this provide any clues about the function of the sequence?Why a multiple sequence alignment is needed for researchers? What inferences can be derived from this kind of sequence alignments? Explain two extreme cases that are non-informative for the multiple sequence alignment.
- write down the applications of pair wise and multipal sequence alignment in the field of bioinformatics. Enlist some softwares used to perform alignment. Plz enlist at least 10 to 15 points for applicationYou wish to align a 300 bp nucleotide sequence to a genome. Which of the following pairwise sequence alignment algorithms is BEST suited for this task? Global alignment or Local alignment? Please explain or elaborate why you chose this alignment algorithm.Briefly describe the applications of SNPs in DNA typing.