How do shotgun and directed sequencing differ? Why is coverage an important issue?

Q: What are the five main steps in DNA cut-and-paste transposition?

A: The "cut and paste" method is used for saving conversion. The enzyme transposase acts as a pair of…

Q: what are the purpose of sequence alignment? define local alignment and global alignment?

A: Alignments are an effective method for comparing similar DNA or protein sequences. DNA molecules are…

Q: Within genomics, genetic engineering and gene therapy are two topics that are quite comparable. What…

A: Genomics is the study of an organism's entire genetic complement (the genome). It sequences,…

Q: What is the difference of intragenic and intergenic regions? Please explain with drawing.

A: In the intricate tapestry of the genome, the terms "intragenic" and "intergenic" encapsulate…

Q: What is knockdown gene analysis? How is this different from knockout analysis?

A: Gene knockdown is a method in which temporarily stop or decrease the expression of one or more…

Q: What types of cells are used for cloning rDNA?

A: rDNA is called recombinant DNA which contains DNA from multiple sources. Recombinant DNA is it's the…

Q: What is the difference between using genome build hg18 and hg19 in Genome-wide SNP arrays?

A: SNP (Single nucleotide protein) array is a type of DNA (deoxyribonucleic acid) microarray which is…

Q: How is exome sequencing helps in identifying mutations?

A: Exome sequencing refers to the genomic technique in which the sequencing of all the protein-coding…

Q: What does whole exome sequencing reveal?

A: Molecular biology techniques are the techniques that utilize the genetic material of an organism…

Q: What is restriction fragment length polymorphism and which method do we use to detect it?

A: Restrictions length polymorphism (RFLP) is a kind of polymorphism that outcomes from variety in the…

Q: Should the exposome field focus exclusively on measuring chemicals derived from exogebeous sources…

A: The term "exposome" describes all of an individual's lifetime environmental exposures, including…

Q: Outline different strategies for identifying gene sequences.

A: Genome is the study of all genes present in the organism. Gene is a unit of heredity that is…

Q: How many male/female sheep are needed to clone one? Cancloning be done by using adult cells?

A: One male and one female sheep is required to clone one because we need one male gamete and one…

Q: What class of genes is used in MLST analyses?

A: MLST refers to multilocus sequence typing. MLST involves higher frequency of recombination in…

Q: How are dideoxynucleotide triphosphates utilized in sequencing?

A: The chain elongating inhibitors of the DNA polymerase which are required for the Sanger method of…

Q: What is CRISPR? Give two applications for this technology.

A: CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a family of…

Q: What is a single-nucleotide polymorphism (SNP)? How are SNPs used in genomic studies?

A: Single nucleotide polymorphisms ( SNPs) are a type of polymorphism that involves a single base pair…

Q: How have GWAS's changed the field of genomics and what do they allow that other methods do not? What…

A: Introduction :- Genomics is a field of biology that focuses on the study of the structure, function,…

Genetic Evolution

Sexual reproduction produces distinct population variations. Heredity determines the traits and qualities to be passed down to the progeny. Over time, this variation within-species is also affected by the process of human evolution. The study of how genetic variation leads to evolutionary changes is known as genetic evolution. If a trait helps an organism to survive and reproduce, it is more likely to be passed down the generations. It is rare that such traits result in a completely distinct set of traits in descendants than the ancestral population; this can result in the emergence of a new species.