Experiments show that mutations at gene E lead to non-repressible transcription of trp genes. Why?

Q: Inversion of an enhancer region does not affect gene expression, but inversion of the promoter…

A: Key references:Bozhilov, Y. K., Downes, D. J., Telenius, J., Marieke Oudelaar, A., Olivier, E. N.,…

Q: What could be the effect  of a base substitution which prevents post-transcriptional removal of an…

A: A base substitution is a genetic mutation where a single nucleotide base is changed in the sequence…

Q: How would a mutation which prevented Gal3 from binding to Gal80 affect gene expression from the GAL…

A: Galactose metabolizing genes express themselves in the presence of galactose. Galactose is…

Q: What are Suppressor mutations in tRNA genes?

A: Mutation is the sudden heritable changes that occur in the DNA sequences due to error while copying…

Q: Describe some of the ways in which mRNAs might regulate gene expression. What is the role of poly(A)…

A: mRNA (Messenger RNA) is formed by the process of Transcription. Then this mRNA further translated to…

Q: Explain why mutations in the lacI gene are trans in their effects, but mutations in the lacO gene…

A: Lac operon is defined as an operon which is required for the metabolism and transport of a lactose…

Q: How does RNA regulate gene expression? Specifically what is the pathway siRNA and miRNAs regulate…

A: The genes are expressed when the genetic codes of the DNA are fully converted into the protein…

Q: Transcriptional regulation often involves a regulatory protein that binds to a segment of DNA and a…

A: The process involved in regulating copying of instruction from the DNA into RNA is called…

Q: If a mutation occurred in the pRM promoter that rendered this promoter as ‘nonfunctional and unable…

A: Promoter sequence is present in the upstream of the gene sequence , is the part of dna where rna…

Q: Explain the imporatance of TATA box of in transcription ?

A: Transcription : It is a process of making RNA copy from DNA template strand. RNA is directly…

Q: If a gene is repressible and under positive control, what kind of effector molecule and regulatory…

A: Gene regulation vary in prokaryotes and eukaryotes. Prokaryotic genes regulation may administrated…

Q: During certain stages of cell growth, the requirement for certain gene products may require gene…

A: Gene amplification is the rise in amount of a specific portion of the genome differentially, in…

Q: (a) Did deletion of any of the possible control elements cause anincrease in reporter gene…

A: Insertion and deletion are naturally processes occurring within the DNA or mRNA sequence for…

Q: How do we know that expression of the information encoded in DNA involves an RNA intermediate?

A: The genetic material of the cell, that is, the DNA (deoxyribonucleic acid) comprises various genes…

Q: Explain how cells prevent excess transposable elementmobilization

A: Transposable elements (TEs) are the small segments of DNA that can move from one position to other…

Q: ith examples explain the importance of Non-coding ribonucleic acid interference in regards to gene…

A: A DNA sequence's genes are translated into amino acid sequences during the process of gene…

Q: The functioning of enhancers is an example of(A) a eukaryotic equivalent of prokaryotic promoter…

A: Enhancer refers to a short region of DNA. It increases the process of transcription of a particular…

Q: What is the effect of supper repressor (lacI^s) mutations?

A: Lac operon is a transcriptionally regulated system in E.coli which enables the bacteria to utilize…

Q: Some mutations in the trp 5′ UTR increase termination by the attenuator. Where might these mutations…

A: Tryptophan operon consists of a leader region located at the 5' terminal of mRNA called 5' UTR. The…

Q: Using three examples, describe how allosteric sites are important in the function of genetic…

A: Enzymes are proteinaceous catalysts that are genetically encoded by the cell often present with…

Q: Predict and explain the effect on GAL1 transcription, in the presence of galactose alone, of the…

A: Note: Hi! Thank you for the question. As per the honor code, we are allowed to answer three…

Q: Explain in detail the role of super-enhancers. Give some examples. How the super-enhancers can be…

A: There are trillions of cells in the physical structure. They give the body structure, absorb…

Q: . What type of mutation of the lac repressor might be both constitu- tive and trans-dominant?

A: Trans-Dominant- A mutation in a regulatory gene that can control the expression of a structural gene…

Q: If a mutation prevented IRP from binding to the IRE in the ferritin mRNA, how would the mutation…

A: Ferritin is an iron-containing protein that is the primary source of iron stored inside the cells.…

Q: Compare the control of gene regulation in eukaryotes and prokaryotes at the level of initiation of…

A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…

Q: Mutations that occur at the end of a gene may alter the sequence of the gene and prevent…

A: Transcription is one of the defined steps of gene expression and precisely refers to the formation…

Q: whose expression is affected by regulatory mutations?

A: Mutation-These are sudden changes in the gene expression which can alter the expression of…

Q: What do we mean when we say that OC mutations in thelac system are cis-acting?

A: Introduction When a DNA gene is destroyed or altered in such a way that the genetic message carried…

Q: Enhancers contain binding sites for transcription factors that regulate transcription. are…

A: Enhancers  Enhancers are found in the upstream of DNA. They are short sequence about 50 to 1500 base…

Q: RNAP can access the lacZ promoter irrespective of whether CAP-CAMP is binding the CAP o True False

A: Lac operon is a set of structural genes regulated by a common promoter. It is found in bacteria.

Q: Consider the CT/CGRP example of alternative splicing. Which different types of alternative splicing…

A: Alternative splicing is a technique that allows messenger RNA (mRNA) to control the production of…

Q: Mutations in bacterial promoters may increase or decrease the rate of gene transcription. Promoter…

A: In bacterial promoters, the sequence of the -10 site is critical for binding of RNA polymerase and…

Q: noticed that the bacterial gene for actin; which has 375 amino acids, has had a mutation at the 25th…

A: The changes in DNA nucleotides due to environmental conditions like exposure to radiation or UV…

Q: If a nonsense mutation can be suppressed by a tRNA mutation that changes an anticodon so that a…

A: Mutations are defined by any changes in the original DNA sequence caused due to insertions,…

Q: Describe ways to achieve post-transcriptional control of gene expression

A: Transcription is the process in which RNA is transcribed with the help of the DNA template. In the…

Q: What are the two main components to activation of transcription via epigenetic mechanisms?

A: Transcription is the process of converting double-stranded DNA into single-stranded RNA with help of…

Q: State whether each of the following would be likely to (generally) increase or decrease the…

A: Gene expression regulation involves the modification of both the DNA and the packaging proteins…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.