Elimination Reactions Predicting the product of an elimination reaction Draw one product of an elimination reaction between the molecules below. Note: There may be several correct answers. You only need to draw one of them. You do not need to draw any of the side products of the reaction. ㅁ ☐ :☐ + X G P + HO Click and drag to start drawing a structure. 1/5
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- Part A Draw a mechanism for this reaction: NN HO A OH H₂C CH₂ Edit the reaction by drawing all steps in the appropriate boxes and connecting them with reaction arrows. Add charges where needed. Electron-flow arrows should start on an atom or a bond and should end on an atom, bond, or location where a new bond should be created. H EXP. CONT H₂C CH₂ Marvin JS by ChemAxon H Z O N O S CI Br I P FDraw the major product to each of the following reactions.Identify the major product of the following reaction sequence. 1) [H*], H₂NNH2, (-H₂O) 2) KOH/H₂O, heat HO₂C HO₂C HO CO,H OH OH There is no reaction under these conditions or the correct product is not listed here.
- In each reaction box, place the best reagent or reactant from the list below. Reagents may be used more than once or not at all. Draw the intermediate products B and C (both are neutral; omit byproducts).draw the reaction, including reactants, reagents and products.Draw the major organic product of the following reaction: SOCI, OH • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • If the given reaction has more than one step, give only the final product. • In cases where there is more than one answer, just draw one. • Do not include lone pairs in your answer. They will not be considered in the grading. C P opy aste ChemDoodle
- Part A and BPlease explain the chosen letter. In the sequence of reactions below, A and B are which of the following? o NaCN, (HCl) H3O+ →B (CH3),CO- A- A а. (CН3)2C(ОН)CN, (CH3)2C(ОH)соон b. (CH3)2C(ОН)CN, (CH3)2C (ОН)2 с. (CНз)2C(ОH)CN, (CH3)2CHCOОН d. (CH3)2C(OH)CN, (CH3)2C=OBr CH3OH + Br-Br H3CO The mechanism proceeds through a first cationic intermediate, intermediate 1. Nucleophilic attack leads to intermediate 2, which goes on to form the final product. In cases that involve a negatively charged nucleophile, the attack of the nucleophile leads directly to the product. +Br + CH3OH Br Intermediate 1 Intermediate 2 (product) In a similar fashion, draw intermediate 1 and intermediate 2 (final product) for the following reaction. OH + Br2 + HBr Br racemic mixture • Pay attention to the reactants, they may differ from the examples. In some reactions, one part of the molecule acts as the nucleophile. • You do not have to consider stereochemistry. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate intermediate 1 and intermediate 2 using the → symbol from the dropdown menu.
- 3. Both El and E2 reactions are possible with 3° alkyl halides. Which elimination mechanism would be favored by the base NaOH? Show the curved arrow mechanism leading to both regioisomers. Draw the energy diagram for this reaction and include the transition state structure leading to each of the possible products. Indicate which one would be favored and use the energy diagram to explain your reasoning. How would you favor the other regioisomer? Br z odd NaOHDraw the reactant of the following reaction sequence.Draw the major organic product of the reaction shown below. OH CH3 H₂SO4 • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • In cases where there is more than one answer, just draw one. ▾ Sn [F ? ChemDoodleⓇ ба