1. Propose a mechanism for each of the following reactions. MeO H KOH, H₂O CN 45 °C OH H3O+ 95 °C H

Propose a mechanism for the following reaction. Draw out the each step of the reaction including ALL intermediates. CI A CO₂ Et + inte NaO6t EtOH CTS Eta₂c,

Q13

Nonconjugated , -unsaturated ketones, such as 3-cyclohexenone, are in an acid-catalyzed equilibrium with their conjugated , -unsaturated isomers. Propose a mechanism for this isomerization.

All rearrangements we have discussed so far have involved generation of an electron-deficient carbon followed by a 1,2-shift of an atom or a group of atoms from an adjacent atom to the electron-deficient carbon. Rearrangements by a 1,2-shift can also occur following the generation of an electron-deficient oxygen. Propose a mechanism for the acid-catalyzed rearrangement of cumene hydroperoxide to phenol and acetone.

Draw a structural formula for the major organic product of each reaction and specify the most likely mechanism by which each is formed. (g) CH3CH2ONa++CH2=CHCH2Clethanol

Complete each reaction scheme below with the starting material required to give the product shown as the only major product following the indicated sequence of reactions. Each individual reaction in the sequence must serve a purpose and must result in a product that is different from the corresponding starting material. 1) i) LIAIH, ii) H30* 2) TSCI, pyridine OTs

In EAS bromination reactions, a -NHCOCH3 substituent on the aromatic ring is: O an activator and an o,p-director. O a deactivator and a m-director. an activator and a m-director. NHCOCH3 catalyzes the 1,2 addition of bromine across the double bond O a deactivator and an o,p-director.

How do I make a mechanism for this reaction

Classify the following reaction as an Sn1, Sn2, E1, E1cB, E2 reaction. Can you show me the leaving group and explain how to find a leaving group? And how to identify the other reactions?