Duchenne Muscular Dystrophy (DMD) is a sex- linked, recessive disease in which a mutation in the gene for dystrophin results in muscle cell degeneration. A normal man marries a woman who is a carrier for DMD. a) What are the parent genotypes? b) What are the four possible offspring genotypes from this cross? HINT - do a Punnett Square to figure this out! c) If they have four sons, how many of them will have DMD? C d) If they have eight children, how many will be carriers of DMD? BONUS (+1): Why are males more often affected by sex-linked disorders than females?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Duchenne Muscular Dystrophy (DMD) is a sex-
linked, recessive disease in which a mutation in
the gene for dystrophin results in muscle cell
degeneration. A normal man marries a woman
who is a carrier for DMD.
a) What are the parent genotypes?
b) What are the four possible offspring genotypes
from this cross? HINT - do a Punnett
Square to figure this out!
c) If they have four sons, how many of them will
have DMD? (
d) If they have eight children, how many will be
carriers of DMD?
BONUS (+1): Why are males more often affected
by sex-linked disorders than females?
Transcribed Image Text:Duchenne Muscular Dystrophy (DMD) is a sex- linked, recessive disease in which a mutation in the gene for dystrophin results in muscle cell degeneration. A normal man marries a woman who is a carrier for DMD. a) What are the parent genotypes? b) What are the four possible offspring genotypes from this cross? HINT - do a Punnett Square to figure this out! c) If they have four sons, how many of them will have DMD? ( d) If they have eight children, how many will be carriers of DMD? BONUS (+1): Why are males more often affected by sex-linked disorders than females?
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