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Drugs that block monoamine oxidase activity can be used to A. Increase the release of neurotransmitter into the synaptic space B. Increase the levels of neurotransmitter available for release C. Increase the activity of neurotransmitter synthesizing enzymes D. Increase the degradation of neurotransmitters within axon terminals

Drugs that block monoamine oxidase activity can be used to A. Increase the release of neurotransmitter into the synaptic space B. Increase the levels of neurotransmitter available for release C. Increase the activity of neurotransmitter synthesizing enzymes D. Increase the degradation of neurotransmitters within axon terminals

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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### Question on Monoamine Oxidase Inhibitors: **Drugs that block monoamine oxidase activity can be used to:** - **A.** Increase the release of neurotransmitter into the synaptic space - **B.** Increase the levels of neurotransmitter available for release - **C.** Increase the activity of neurotransmitter synthesizing enzymes - **D.** Increase the degradation of neurotransmitters within axon terminals **Explanation:** When monoamine oxidase (MAO) activity is inhibited, the breakdown of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine is reduced. This results in higher levels of these neurotransmitters in the brain, which can be beneficial in treating certain mood disorders. Therefore, MAO inhibitors (MAOIs) are commonly used in the treatment of depression and anxiety disorders. In terms of the options presented: - **Option A and B** are relevant as they relate to increasing neurotransmitter availability or release. - **Option C** involves increasing enzyme activity, which is not the primary function of MAO inhibitors. - **Option D** suggests increased degradation, which is the opposite effect of what MAO inhibitors actually do. Typically, the correct answer would emphasize increasing neurotransmitter availability or release.
Transcribed Image Text:### Question on Monoamine Oxidase Inhibitors: **Drugs that block monoamine oxidase activity can be used to:** - **A.** Increase the release of neurotransmitter into the synaptic space - **B.** Increase the levels of neurotransmitter available for release - **C.** Increase the activity of neurotransmitter synthesizing enzymes - **D.** Increase the degradation of neurotransmitters within axon terminals **Explanation:** When monoamine oxidase (MAO) activity is inhibited, the breakdown of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine is reduced. This results in higher levels of these neurotransmitters in the brain, which can be beneficial in treating certain mood disorders. Therefore, MAO inhibitors (MAOIs) are commonly used in the treatment of depression and anxiety disorders. In terms of the options presented: - **Option A and B** are relevant as they relate to increasing neurotransmitter availability or release. - **Option C** involves increasing enzyme activity, which is not the primary function of MAO inhibitors. - **Option D** suggests increased degradation, which is the opposite effect of what MAO inhibitors actually do. Typically, the correct answer would emphasize increasing neurotransmitter availability or release.
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