Drug X is a new experimental drug. After IV bolus administration of 200 mg of drug X to a healthy volunteer, 180 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 50 mg•hr/L. After oral dose administration of 400 mg of drug X to the same volunteer, 270 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 75 mg•hr/L. Determine the hepatic clearance values of drug X in L/hr. Please round to the nearest tenth and do not include units.
Drug X is a new experimental drug. After IV bolus administration of 200 mg of drug X to a healthy volunteer, 180 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 50 mg•hr/L. After oral dose administration of 400 mg of drug X to the same volunteer, 270 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 75 mg•hr/L. Determine the hepatic clearance values of drug X in L/hr. Please round to the nearest tenth and do not include units.
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Drug X is a new experimental drug. After IV bolus administration of 200 mg of drug X to a healthy volunteer, 180 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 50 mg•hr/L. After oral dose administration of 400 mg of drug X to the same volunteer, 270 mg of drug X was recovered in the urine and the calculated AUC from plasma concentration is 75 mg•hr/L. Determine the hepatic clearance values of drug X in L/hr. Please round to the nearest tenth and do not include units.
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