DNA Transcription Pre-mRNA is cleaved, at a position from 11 to 30 nucleotides down- Transcription start site stream of the consensus sequence, Consensus 11-30 in the 3' untranslated region. sequence nucleotides Pre-MRNA 5'| AAUAAA 3' Cleavage U-rich sequence Cleavage site The addition of adenine nucleotides (polyadenylation) takes place at 13' the 3' end of the pre-MRNA, generating the poly(A) tail. 5" AAUAAA Polyadenylation Poly(A) tail MRNA 5' AAUAAA AAAAAAAAAAAAAAAAAAA 3' 14.7 Most eukaryotic mRNAs have a 3' poly(A) tail

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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What would be the most likely effect of moving the AAUAAA
consensus sequence shown in Figure 14.7 10 nucleotides upstream?

DNA
Transcription
Pre-mRNA is cleaved, at a position
from 11 to 30 nucleotides down-
Transcription
start site
stream of the consensus sequence,
Consensus
11-30
in the 3' untranslated region.
sequence nucleotides
Pre-MRNA 5'|
AAUAAA
3'
Cleavage U-rich sequence
Cleavage
site
The addition of adenine nucleotides
(polyadenylation) takes place at
13' the 3' end of the pre-MRNA,
generating the poly(A) tail.
5"
AAUAAA
Polyadenylation
Poly(A) tail
MRNA 5'
AAUAAA
AAAAAAAAAAAAAAAAAAA 3'
14.7 Most eukaryotic mRNAs have a 3' poly(A) tail
Transcribed Image Text:DNA Transcription Pre-mRNA is cleaved, at a position from 11 to 30 nucleotides down- Transcription start site stream of the consensus sequence, Consensus 11-30 in the 3' untranslated region. sequence nucleotides Pre-MRNA 5'| AAUAAA 3' Cleavage U-rich sequence Cleavage site The addition of adenine nucleotides (polyadenylation) takes place at 13' the 3' end of the pre-MRNA, generating the poly(A) tail. 5" AAUAAA Polyadenylation Poly(A) tail MRNA 5' AAUAAA AAAAAAAAAAAAAAAAAAA 3' 14.7 Most eukaryotic mRNAs have a 3' poly(A) tail
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