Dihydrogen phosphate, H₂PO₄⁻(aq), undergoes the following acid base equilibria in blood: H₂PO₄⁻(aq) ⇌ H⁺(aq) + HPO₄²⁻(aq)⇌ H⁺(aq) + PO₄³⁻(aq). The pKa values for the first and second steps are 7.2 and 12.4, respectively. The pH of human blood is 7.37 and this is tightly regulated. Which of the following statements most accurately describes the concentrations of the different species for the above reactions in blood. (Hint, think of the titration curves for H₂PO₄⁻(aq) and HPO₄²⁻(aq) and their respective pKa's.) A) [H₂PO₄⁻(aq)] is much greater than [HPO₄²⁻(aq)] and [PO₄³⁻(aq)] B) [HPO₄²⁻(aq)] is much greater than [H₂PO₄⁻(aq)] and [PO₄³⁻(aq)]. C) [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)] are both present and greater than [PO₄³⁻(aq)]. D) [PO₄³⁻(aq)] is much larger than the other concentrations, [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)]
Dihydrogen phosphate, H₂PO₄⁻(aq), undergoes the following acid base equilibria in blood: H₂PO₄⁻(aq) ⇌ H⁺(aq) + HPO₄²⁻(aq)⇌ H⁺(aq) + PO₄³⁻(aq). The pKa values for the first and second steps are 7.2 and 12.4, respectively. The pH of human blood is 7.37 and this is tightly regulated. Which of the following statements most accurately describes the concentrations of the different species for the above reactions in blood. (Hint, think of the titration curves for H₂PO₄⁻(aq) and HPO₄²⁻(aq) and their respective pKa's.) A) [H₂PO₄⁻(aq)] is much greater than [HPO₄²⁻(aq)] and [PO₄³⁻(aq)] B) [HPO₄²⁻(aq)] is much greater than [H₂PO₄⁻(aq)] and [PO₄³⁻(aq)]. C) [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)] are both present and greater than [PO₄³⁻(aq)]. D) [PO₄³⁻(aq)] is much larger than the other concentrations, [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)]
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Dihydrogen phosphate, H₂PO₄⁻(aq), undergoes the following acid base equilibria in blood: H₂PO₄⁻(aq) ⇌ H⁺(aq) + HPO₄²⁻(aq)⇌ H⁺(aq) + PO₄³⁻(aq). The pKa values for the first and second steps are 7.2 and 12.4, respectively. The pH of human blood is 7.37 and this is tightly regulated. Which of the following statements most accurately describes the concentrations of the different species for the above reactions in blood. (Hint, think of the titration curves for H₂PO₄⁻(aq) and HPO₄²⁻(aq) and their respective pKa's.)
A) [H₂PO₄⁻(aq)] is much greater than [HPO₄²⁻(aq)] and [PO₄³⁻(aq)]
B) [HPO₄²⁻(aq)] is much greater than [H₂PO₄⁻(aq)] and [PO₄³⁻(aq)].
C) [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)] are both present and greater than [PO₄³⁻(aq)].
D) [PO₄³⁻(aq)] is much larger than the other concentrations, [H₂PO₄⁻(aq)] and [HPO₄²⁻(aq)]
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