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Determine the nucleophile and electrophile in this reaction.

Determine the nucleophile and electrophile in this reaction.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Determine the nucleophile and electrophile in this reaction.
lucer and as lx, the willow family of plants, was derived from extracts. In folk medicine, willow bark teas were used as headache remedies and other tonics. Nowadays, salicylic acid is administered in the form of aspirin which is less irritating to the stomach than salicylic acid. To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. In this experiment, phosphoric acid will be used as the catalyst. The excess acetic acid will be quenched with the addition of water. The aspirin product is not very soluble in water so the aspirin product will precipitate when water is added. The synthesis reaction of aspirin is shown below: HO. + H3C H3PO4 но. H3C OH CH3 HO. salicylic acid (C,H,O) acetic anhydride (C,H0,) acetic acid (CH,0,) o=C CH3 acetylsalicylic acid (CH,0) 102 g/ mol 138 g/mol d = 1.08 g/mL 180 g/mol Since acetic acid is very soluble in water, it is easily separated from the aspirin product. The aspirin isolated in this step is the "crude product". A "purified product" can be obtained through recrystallization of the crude product in hot ethanol. In this experiment, the crude product will be the desired product. The percent yield of the crude product will be determined for this reaction. The purity of the product will also be analyzed, The product will be analyzed by three different methods: melting
Transcribed Image Text:lucer and as lx, the willow family of plants, was derived from extracts. In folk medicine, willow bark teas were used as headache remedies and other tonics. Nowadays, salicylic acid is administered in the form of aspirin which is less irritating to the stomach than salicylic acid. To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. In this experiment, phosphoric acid will be used as the catalyst. The excess acetic acid will be quenched with the addition of water. The aspirin product is not very soluble in water so the aspirin product will precipitate when water is added. The synthesis reaction of aspirin is shown below: HO. + H3C H3PO4 но. H3C OH CH3 HO. salicylic acid (C,H,O) acetic anhydride (C,H0,) acetic acid (CH,0,) o=C CH3 acetylsalicylic acid (CH,0) 102 g/ mol 138 g/mol d = 1.08 g/mL 180 g/mol Since acetic acid is very soluble in water, it is easily separated from the aspirin product. The aspirin isolated in this step is the "crude product". A "purified product" can be obtained through recrystallization of the crude product in hot ethanol. In this experiment, the crude product will be the desired product. The percent yield of the crude product will be determined for this reaction. The purity of the product will also be analyzed, The product will be analyzed by three different methods: melting
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