Describe the three domains of a receptor tyrosine kinase. Explain the structure of the transmembrane domain and the amino acid composition and arrangement of this part of the receptor
Q: What are a deletion loop and an inversion loop? What is the importance of these loops during cell…
A: Introduction Mitosis and meiosis are the two kinds of cell division. When people say "cell…
Q: The a-adrenoceptors are subdivided into two subgroups, a1 and a2, based on their response to the…
A: Adrenorecepors are also known by the name of adrenergic receptors. These are divided into two…
Q: Should animals be utilized in viral pathogenesis research? Why or why not? Need at least a full…
A:
Q: Change in gene frequencies within a reproductive population is called: O allopatric speciation. O…
A: Evolution is defined as a change in the inheritable traits of biological populations, over multiple…
Q: Also answer Location number where correspond the 3 end of mRNA from this gene ans where u would find…
A: Exons are nucleic acid coding sequences that can be found in mRNA. Non-coding segments in DNA are…
Q: mystery compound, compound B. You add it to the dish with your hippocampal circuit. You fire the…
A: EPSP is excitatory post synaptic potential which is initiated by the movement of positively charge…
Q: Punctuated Equilibrium is a hypothesis that ... O suggests that evolution is not gradual but occurs…
A: Punctuated equilibrium is a hypothesis that evolution of a species is marked by sudden isolated…
Q: Question 4 of 25 Use the diagram to answer the question. Some organisms use a single loop…
A: The single loop heart is found in lower organisms (fish), in which the blood pressure and oxygen…
Q: (1) List and briefly explain four methods of studying an E-S complex. (2) (a) Which fluorogenic…
A: Answer 1: four methods of studying an enzyme substrate complex are : 1.enzyme and substrate present…
Q: What ions are removed from the uremic plasma? Mark all that apply Na+ K+ CI- Ca+2
A: Due to inadequate excretory, regulatory, and endocrine function of the kidneys results in uremic…
Q: marine-plastics-pollution suluton in a
A: Pollution is the introduction of any material (solid, liquid, or gas) or form of energy (such as…
Q: Most inherited forms of cancer involve _______________ and these individuals are for the mutation.…
A: Firstly we can examine what each of the terms given represents. 1. Tumor suppressor gene: It is a…
Q: of the following is not an example of green infrastructu Pavement Bioswales Bioretention Planter…
A: Lack of greenery has made the life difficult. In order to promote greenery and conserve water, green…
Q: Simple Diffusion 1. 2. 3. 1. 2. 3. 23 Restrictive Diffusion
A: Diffusion is defined as "the movement of molecules along a concentration gradient from an area of…
Q: Members of some species will sound warning calls when they notice predators even though this…
A: In this statement, the individual making alarm noise is not being provided a survival advantage…
Q: B) Migration is a one-way movement. C) Because their offspring return to the ocean, the entire…
A: Salmon are considered “anadromous” which means they live in both fresh and salt water. These are…
Q: of
A: The main purpose to do homogenization of the milk is to break the large fat globules and then create…
Q: 24. During the disassembly of a nucleosome which part of the nucleosomes is the first to be removed.…
A: The capacity of nucleic acids to guide their own reproduction from monomers makes them unique.…
Q: 6. a) What is meant by the term "symbiosis"? [K/U] b) Give an example for each type of symbiosis and…
A: Animals breathe in oxygen and exhale carbon dioxide during the process of respiration. Plants, on…
Q: benefits of 1 vs 2 loop circulation system, benefits of 4 chambered vs 3 vs 2 chambered heart
A: One loop circulatory system has only obe circuit . In Single circuit circulation blood flows…
Q: What is the main reason for archiving your phage? so that you could repeat the DNA isolation (for…
A: The answer is to store your phage long term so that anyone who accesses the phage database could…
Q: a certain family with both parents affected with Heberdon’s nodes, a single gene trait characterized…
A: There are many four different modes of inheritance autosomal dominant, autosomal recessive, X linked…
Q: Central self-tolerance in the immune system arises when maturing T cells in the thymus undergo…
A: Apoptosis is a process of natural cell death. T cells are matured in Thymus but are born in Bone…
Q: Choose 1 biotechnology product in the field of medicine. Provide a 1-2 minute monologue about this…
A: The relationship between science and health services is that science creates medicine and methods of…
Q: Sickle cell 1). how many people does it affect? 2) Is it genetic and if so what chromosome is the…
A: The sickel cell anemia is a genetic disease and a large amount of population is affected by this…
Q: How does we know that trees or plants are transpiring base on your experiment?
A: The physiological process by which water is lost in the form of vapour from the living tissues of…
Q: What are the principle and basic concepts of GRAM STAIN?
A: Gram staining is among the most important microbiology staining procedures. It was first invented in…
Q: A classical experiment studying the fate determination of stem cells in the developing embryo uses…
A: Answer :- Option ( D) is correct. - The organs arising from quail somites develop in the reverse…
Q: A 150₁ 100- Cell-to-cell transmission (Relative, %) U D SARS-CoV SARS-CoV-2 Cell-to-cell…
A: Covid Pandemic Covid-19 is the recent cause of pandemics globally. It is a viral infectious disease…
Q: Consider the processes associated with a lake, which of the following statements is true? Organic…
A: Lakes are bodies of water enclosed by land and are found in diverse habitats such as mountains,…
Q: What is the role of lactic acid? It is converted to pyruvic acid through glycolysis. It is a…
A: Introduction Lactic acid is an integral part of the human body, it is is a chemical byproduct of…
Q: What types of cells are used for cloning rDNA?
A: rDNA is called recombinant DNA which contains DNA from multiple sources. Recombinant DNA is it's the…
Q: What are the principle and basic concepts of SMEAR PREPARATION? (please explain it thoroughly in a…
A: Introduction A smear is a small amount of culture spread in a very thin film on the surface of the…
Q: What are the categories of body shape and why is fat distribution monitored in the elderly?
A:
Q: You are studying a pathogenic bacterium which secretes a toxin that affects G protein receptor…
A: The cAMP signaling pathway, commonly referred to as the adenylyl cyclase pathway, is a cell…
Q: Explain why it is not always a good idea for an elderly person to lose weight, even if they have a…
A: Body mass index (BMI) is a screening tool that measures the ratio of your height to your weight.…
Q: The effects of on the CNS may lead to convulsions when high doses are used. O Ach O Neostigmine O…
A: A convulsion is a broad term for involuntary muscle contractions. Epileptic seizures, febrile…
Q: 8. Describe the MAP kinase activation pathway
A: Protein kinases and other messenger systems form highly interactive networks to achieve the…
Q: Identify if the following statements are true or false. Quantitative PCR is also known as the…
A: A real-time polymerase chain reaction is a molecular genetics lab technology that involves the…
Q: Explain how the activities of endocrine glands are regulated. 250 word count in own words thank you
A: Introduction :- The endocrine system is made up of hormone-producing glands. Hormones are the…
Q: found on ganglia of the peripheral nervous system and on the autonomic effector organs are…
A: Cholinergic receptor is of two types: Nicotinic and muscarinic receptor.
Q: What is corpus luteum. How does it function as an endocrine gland?.
A: The female reproductive apparatus retains an egg, and the sperm is discharged into the female body…
Q: hoose the letter of the correct answer. Please answer it both. 1. Which of these is the major…
A: The process of creating offspring which are physiologically or biologically identical to the parent…
Q: Purified proteins can have their mW determined by: Ethanol precipitation O SDS-PAGE O going to taco…
A: The application of scientific and technical principles to the processing of the material by…
Q: STUDY QUESTIONS 1. List down at least 3 differences in the anatomy of male and female frogs. 2. How…
A: Frogs are amphibians and humans are mammals.
Q: Question: Match the following terms with their meanings from the drop down menus. Water potential…
A: Introduction Cell transports are the movement of a substance through the cell membrane. The…
Q: Please state the step-by-step procedure of SMEAR PREPARATION? (please explain it thoroughly in a…
A: The preparation of a smear is required for various lab procedures, including the Gram-stain. The…
Q: You are studying a cell line that expresses both GPCR-A and GPCR-B, each receptor binds the same…
A: The G-protein couples receptor signalling is mediated by a seven pass transmembrane receptor located…
Q: Recall that the alleles for blood groups are A, B, O, and that A and B are each dominant to O, and A…
A: The genetic makeup of living organisms is referred to as genotype. The total number of genes passed…
Q: Explain why this statement is true, using phylogenetic and morphological evidence. Tunicates…
A: Tunicates are transparent or brilliantly colored marine animals that are found on the dock pilings,…
2. Describe the three domains of a receptor tyrosine kinase. Explain the structure of the transmembrane domain and the amino acid composition and arrangement of this part of the receptor
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- Which of the following is incorrect about pathways activated by G-proteincoupled receptors? a. The extracellular signaling molecule is the first messenger. b. When activated, plasma membrane-bound G protein canswitch on an effector. c. Second messengers enter the nucleus. d. ATP converts to cAMP to activate protein kinases. e. Protein kinases phosphorylate molecules to change cellularactivity.6. Define a receptor tyrosine kinase and distinguish it from a serine/threonine kinase. (As we discuss ANY kinase in signalling pathways, pay close attention to what type of kinase it is...does it phosphorylate serene/threonine resides or tyrosine residues?)3. When you think about the primary structure of the mannose-6-P receptor, assuming that it is an integral membrane protein with one membrane-spanning domain and assuming that it has a ERSS, what are all of the different protein domains that must be present in this protein's primary structure to get it to where it needs to go and to carry out all of the functions/activities? (Draw a schematic of the protein structure/sequence and explain each region).
- . which of the following statements about heterotrimetric G proteins and their receptors is incorrect? A: when GTP binds to the alpha subunit of the G protein, the beta-gamma subunit dissociates from the alpha subunit B: G-protein coupled receptors contain nine transmembrane alpha helices C: binding of arrestin causes removal of the receptor from the membrane D: G protein- coupled receptors may be desensitized by serine phosphorylation I had chosen option A and got it wrong. What is the Correct answer and explain how it is. Also, where did i go wrong in choosing option A?3. How does dimerization of a receptor tyrosine kinase promotes autophosphorylation of the intracellular domain of the receptor? How does the formation of a dimer helps the phosphorylation reaction?4. Describe where is the phosphate group added on a protein when it gets phosphorylated (what amino acid? what atom?). Then list all the ways that protein function may change after it gets phosphorylated PLEASE ANSWER BOTH1. Based on the following description, draw the cell signaling pathway described (you only need to draw the pathway in one cell, but show the type of signaling described – you may need 2 diagrams). Compound X is released from cells in the pancreas and activates cells in the liver. What general type of cell signaling is this? When compound X binds its receptor on a liver cell, some of the amino acids (Y – one letter amino acid code) on the cytoplasmic side of the receptor are phosphorylated. Label what type of receptor this is. This leads to the receptor activating a cytoplasmic protein F which then activates a kinase K which then activates protein Z (diagram what is happening here – how is protein Z activated). Protein Z activation results in several genes being expressed. Label all your parts (don’t forget to label the ligand). Circle the signal transduction pathway and put a box around the cell response.
- Describe the 3 main steps for activation of receptor tyrosine kinases.10. A scientist working in a research laboratory has been examining different agonists of serotonin receptor 1B (5-НT1B), а G-protein-coupled re- ceptor. Compound A has a much higher affin- ity for 5-HT1B than compound B. Both com- pounds have a higher affinity for the receptor than serotonin. Which of the following de- scribes the relationship between compound A and compound B when considering the guan- ine-nucleotide exchange activity of 5-HT1B? (A) Km for the exchange reaction with com- pound A is higher than that with com- pound B (B) Km for the exchange reaction with com- pound A is lower than that with compound (C) Km values with compounds A and B1. What cellular event happens in response to the binding of a growth factor to its respective receptor on the membrane of the growth factor’s target cell? Describe what happens to a tyrosine kinase receptor once it binds the growth factor signal. 2. Describe the three domains of a receptor tyrosine kinase. Explain the structure of the transmembrane domain and the amino acid composition and arrangement of this part of the receptor PLEASE ANSWER BOTH
- 2 of 16 Compound Binds to Elicits biological receptor response A Yes Yes B Yes No C No No Refer to the table above. Compound X is the natural ligand that binds to a receptor and stimulates a signal transduction pathway associated with the receptor. Based on the information given in the table, what are the roles of compounds A, B, and C? O A is an antagonist, B is an agonist, and C is a ligand. A is an agonist, B is an antagonist, and C has no role. A is a ligand, B has no role, and C is an antagonist. A is an agonist, B is an antagonist, and C is an agonist. A has no role, B is an agonist, and C is an antagonist.7. Fill in the table below, outlining different aspects of glutamate singlaing in the mammalian brain. A legend of possible entries is provided below the table, specifically for the columns "marker genes", “associated G proteins" and "ionotropic targets" Marker gene Ionotropic receptors Possible associated G proteins Gs Gą G₁/Go Possible marker genes: Choline acetyltransferase Solute carrier family 17 Glutamate decarboxylase Dopamine ß hydroxylase Possible ionotropic targets: Cayl channels Cav2 channels GIRK channels M-type K¹ channels BK channels SK channels Metabotropic Associated receptors G protein mGluR 1,5 mGluR 2-4,6-7- Pre- or post- Ionotropic Neuronal effects synaptic action? target(s) Tryptophan hydroxylase 2 Tyrosine hydroxylase Histidine decarboxylase27) One of the main differences between receptor tyrosine kinase (RTK) signaling and G-protein coupled receptor (GPCR) signaling is that: GPCR signaling involves enzyme cascades, while RTK signaling does not. Only RTK signaling involves kinase activity. Only GPCR signaling involves a GTPase. GPCR signaling is more likely to have a short-term, reversible effect.