Darwin’s insights into the role of selection in evolution began with close observations of the enormous phenotypic variation among different pure-breeding varieties of domesticated pigeons.  Study of varieties found in any domesticated species could provide similar insights.  For comparison, we’d like to know what degree of phenotypic variation might be expected among the domesticated peas available to Mendel. a. Starting with an F1 hybrid heterozygous for phenotypically distinguishable allele pairs (one of which is completely dominant to the other) at 7 genes, how many different phenotypes would be expected in the F2 generation? b. It might take a large number of F2 individuals to observe all of these phenotypic combinations, depending on the frequency of the rarest phenotype.  What is the expected rarest phenotype and what it its expected frequency among the F2 individuals? c. How many different phenotypes could have been observed in the F2 generation if all of the allele pairs of the 7 genes were incompletely dominant? (Note: it would not take a larger population to observe all of them than in part a – why not?)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Darwin’s insights into the role of selection in evolution began with close observations of the enormous phenotypic variation among different pure-breeding varieties of domesticated pigeons.  Study of varieties found in any domesticated species could provide similar insights.  For comparison, we’d like to know what degree of phenotypic variation might be expected among the domesticated peas available to Mendel.
a. Starting with an F1 hybrid heterozygous for phenotypically distinguishable allele pairs (one of which is completely dominant to the other) at 7 genes, how many different phenotypes would be expected in the F2 generation?
b. It might take a large number of F2 individuals to observe all of these phenotypic combinations, depending on the frequency of the rarest phenotype.  What is the expected rarest phenotype and what it its expected frequency among the F2 individuals?
c. How many different phenotypes could have been observed in the F2 generation if all of the allele pairs of the 7 genes were incompletely dominant? (Note: it would not take a larger population to observe all of them than in part a – why not?)
d. In the F10 generation from the above hybrid, how many phenotypically distinguishable pure-breeding varieties could be observed?

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