D 1.0. 0.5- O 6. Answer the questions below about hemoglobin and myoglobin. a. Sketch and label the binding curves of Mb, Hb, and Hb below. b. In the scenarios below for Hb, indicate what effect they would have on the binding curve and give a brief explanation? Scenario Decrease in the concentration of carbon dioxide (CO₂) Distal histidine (the histidine that aids in molecular oxygen binding) mutation to phenylalanine High heat and extreme pH changes Predict if the normal binding curve of Hb will shift right (Hbt), left (Hb), completely to Mb, or no longer bind oxygen completely? Brief Explanation

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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e
1.0
0.5-
0
6.
Answer the questions below about hemoglobin and myoglobin.
a. Sketch and label the binding curves of Mb, Hb, and Hb below.
pº₂
b. In the scenarios below for Hb, indicate what effect they would have on the
binding curve and give a brief explanation?
Scenario
Decrease in the
concentration of
carbon dioxide
(CO₂)
Distal histidine
(the histidine that
aids in molecular
oxygen binding)
mutation to
phenylalanine
High heat and
extreme pH
changes
Predict if the normal binding
curve of Hb will shift right
(Hbt), left (HbⓇ), completely
to Mb, or no longer bind
oxygen completely?
Brief Explanation
Transcribed Image Text:e 1.0 0.5- 0 6. Answer the questions below about hemoglobin and myoglobin. a. Sketch and label the binding curves of Mb, Hb, and Hb below. pº₂ b. In the scenarios below for Hb, indicate what effect they would have on the binding curve and give a brief explanation? Scenario Decrease in the concentration of carbon dioxide (CO₂) Distal histidine (the histidine that aids in molecular oxygen binding) mutation to phenylalanine High heat and extreme pH changes Predict if the normal binding curve of Hb will shift right (Hbt), left (HbⓇ), completely to Mb, or no longer bind oxygen completely? Brief Explanation
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