✓ Correct At pll 7.2 the glutamic acid (Glu) side chain will carry a charge of -1 (at 3 pH units above the pK, for Glu the side chain will be almost fully ionized whereas the histidine (Hid) side chain will carry a charge of < 0.5 (at pH-PK, the charge on His would be 0.5 since pH 7.2 is above its pK, it will carry less (+) charge as it becomes more deprotonated). As the pll increase to 7.9, the charge on Glu will remain-1 and the charge on His will decrease thus, this salt bridge is predicted to become weaker as pll is raised from 72 to 79 Part B Antify your answer with calculations of partial charges on these amino acid side chains at pll- 7.2. (Hint: Consider lessons from Coulomb's law, and the Henderson Hasselbalch equation) Express your answers using two significant figures separated by a comma
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
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