Consider two enzymes catalyzing two reactions (A --> B --> C ) in a metabolic cascade with their properties summarized below: Keg (for reaction) Enzyme Reaction KM Kcat / KM |102 M-1s-1 108 M-15-1 1 A --> B 1 1 mM B --> C 10 10 mM Initial concentrations are [A] = 0.1 mM and [B] = [C] = 0 and both enzymes are %3D present at concentrations of 1 mM. After waiting for 1 ms, the concentrations of A, B, and C are measured. How do you expect the concentrations to be ordered? [B] > [A] > [C] [C] > [B] > [A] [A] > [B] > [C] O [A] > [C] > [B] O [C] > [A] > [B]
Consider two enzymes catalyzing two reactions (A --> B --> C ) in a metabolic cascade with their properties summarized below: Keg (for reaction) Enzyme Reaction KM Kcat / KM |102 M-1s-1 108 M-15-1 1 A --> B 1 1 mM B --> C 10 10 mM Initial concentrations are [A] = 0.1 mM and [B] = [C] = 0 and both enzymes are %3D present at concentrations of 1 mM. After waiting for 1 ms, the concentrations of A, B, and C are measured. How do you expect the concentrations to be ordered? [B] > [A] > [C] [C] > [B] > [A] [A] > [B] > [C] O [A] > [C] > [B] O [C] > [A] > [B]
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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