Substrate 1 Site A Nonpolar Polar and neutral Polar and Site D Site B Polar and neutral Acidic (negatively charged) Basic (positively Site C Polar and neutral Basic (positively charged) 2 Nonpolar
Enzymes are catalytic proteins or RNA molecules that accelerate
are the molecules that are acted upon by enzymes and are converted into products through the
binding of substrates to an enzyme’s active site. Figure 1 below shows a protein enzyme’s active
site and four potential protein substrates. Table 1 indicates the different chemical properties at
several locations in a hypothetical enzyme’s active site, and Table 2 indicates the different
chemical properties at several locations in the potential substrates. Locations labeled “A” in the
enzyme’s active site and on the substrate will attempt to interact, as will locations that are labeled
“B” and “C.
Describe, in terms of energy, how enzymes catalyze chemical reactions.



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