Consider this molecule, which contains one chirality center. What is the highest-priority substituent at this chirality center? ( -CH,CH, -H -CH, -Br What is the lowest-priority substituent at this chirality center? -CH, -H -CH₂CH₂ -Br Name the structure. O(S)-2-bromobutane (R)-2-bromobutane 9 Rotate X Rolata Y C O Rolas Z ОН Zoom in Br Zoom

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### Chirality Center in a Molecule

**Consider this molecule, which contains one chirality center.**

#### What is the highest-priority substituent at this chirality center?

- \(\text{—CH}_2\text{CH}_3\)
- \(\text{—H}\)
- \(\text{—CH}_3\)
- \(\text{—Br}\)

#### What is the lowest-priority substituent at this chirality center?

- \(\text{—CH}_3\)
- \(\text{—H}\)
- \(\text{—CH}_2\text{CH}_3\)
- \(\text{—Br}\)

#### Name the structure:

- \((S)\)-2-bromobutane
- \((R)\)-2-bromobutane

### Diagram Description

On the right side of the page, there is a structure of the molecule consisting of different colored spheres representing different elements:
- **Black** spheres represent carbon (\(\text{C}\)).
- **White** spheres represent hydrogen (\(\text{H}\)).
- **Brown** sphere represents bromine (\(\text{Br}\)).

The 3D molecular structure can be rotated along the X, Y, and Z axes or zoomed in and out for better visualization, which can aid in identifying the chirality center and its substituents.

### Explanation:
In the context of chirality in organic chemistry, the substituent priority at the chirality center is determined using the Cahn-Ingold-Prelog priority rules. The priorities are typically based on the atomic number of the atoms directly attached to the chirality center. The higher the atomic number, the higher the priority.

**Chirality Center:**
A chirality center is typically a carbon atom with four different substituents attached to it, leading to non-superimposable mirror images (enantiomers).

**Carol-Prelog Priority Rules:**
1. **Identify the atoms attached to the chirality center** and rank them based on atomic number; the higher the atomic number, the higher the priority.
2. **If two atoms are the same**, move to the next set of atoms (next atoms in the substituents) and compare their atomic numbers.
3. **Double and triple bonds** are treated as if they are bonded to equivalent single-bonded atoms.

This information will help to determine which substituent has
Transcribed Image Text:### Chirality Center in a Molecule **Consider this molecule, which contains one chirality center.** #### What is the highest-priority substituent at this chirality center? - \(\text{—CH}_2\text{CH}_3\) - \(\text{—H}\) - \(\text{—CH}_3\) - \(\text{—Br}\) #### What is the lowest-priority substituent at this chirality center? - \(\text{—CH}_3\) - \(\text{—H}\) - \(\text{—CH}_2\text{CH}_3\) - \(\text{—Br}\) #### Name the structure: - \((S)\)-2-bromobutane - \((R)\)-2-bromobutane ### Diagram Description On the right side of the page, there is a structure of the molecule consisting of different colored spheres representing different elements: - **Black** spheres represent carbon (\(\text{C}\)). - **White** spheres represent hydrogen (\(\text{H}\)). - **Brown** sphere represents bromine (\(\text{Br}\)). The 3D molecular structure can be rotated along the X, Y, and Z axes or zoomed in and out for better visualization, which can aid in identifying the chirality center and its substituents. ### Explanation: In the context of chirality in organic chemistry, the substituent priority at the chirality center is determined using the Cahn-Ingold-Prelog priority rules. The priorities are typically based on the atomic number of the atoms directly attached to the chirality center. The higher the atomic number, the higher the priority. **Chirality Center:** A chirality center is typically a carbon atom with four different substituents attached to it, leading to non-superimposable mirror images (enantiomers). **Carol-Prelog Priority Rules:** 1. **Identify the atoms attached to the chirality center** and rank them based on atomic number; the higher the atomic number, the higher the priority. 2. **If two atoms are the same**, move to the next set of atoms (next atoms in the substituents) and compare their atomic numbers. 3. **Double and triple bonds** are treated as if they are bonded to equivalent single-bonded atoms. This information will help to determine which substituent has
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