Cisplatin (cis-diamminedichloroplatinum(II)) is the first platinum-basedantitumor agent, and it is still widely used in chemotherapy, whereas thetrans isomer is therapeutically inactive.ClNH3H,NCIAPtВPtCINH3CÍNH3cistrans(cisplatin)a) Assign point group to A and B.b) Is it possible to distinguish A and B based on the Pt-Cl stretchingvibrations using IR and/or Raman spectroscopic data? If so, explain how youcould distinguish them using group theory.

Answered: Image /qna-images/answer/b19d88bf-af98-47e2-a453-94c44af6af78.jpg

Cisplatin (cis-diamminedichloroplatinum(II)) is the first platinum-based antitumor agent, and it is still widely used in chemotherapy, whereas the trans isomer is therapeutically inactive. NH3 H,N CI А В CI NH3 NH, cis trans (cisplatin) a) Assign point group to A and B.

Cisplatin (cis-diamminedichloroplatinum(II)) is the first platinum-based antitumor agent, and it is still widely used in chemotherapy, whereas the trans isomer is therapeutically inactive. NH3 H,N CI А В CI NH3 NH, cis trans (cisplatin) a) Assign point group to A and B.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

7. Consider the C=O stretching data for the following cyclic ketones: cyclopropane 1813 cm³¹; cyclobutanone 1791 cm³¹; cyclopentanone 1740 cm³¹. (a) which ketone has the strongest bond? (b) where in the trend would you expect the C=O stretch of cyclopropenone? (Use the hybridization information in the same way we used hybridization for C-H stretching.)
Pure MSG, a common avor enhancer, exhibits a specic rotation of +24. (a) Calculate the ee of a solution whose [α] is +10. (b) If the ee of a solution of MSG is 80%, what is [α] for this solution?
Draw a picture and determine the point group for EACH of the possible structural arrangements of PFnBr(5-n) for n = 0 to 5. I.e. start with PBr5 and end with PF5. Assuming a static structure, indicate the number and relative intensities of the signals that you would expect to see in the 19F NMR spectrum of each molecule. %3D
Which of the following conjugated systems would have the smallest HOMO-LUMO gap (i.e. largest λ-max of absorbance)? a) 1 b) 2 c) 3 d) 4
4. For the compounds below, fill in the charts of expected integration and multiplicity. Assignment Integration Multiplicity a b C Assignment Integration Multiplicity a b a d e Assignment Integration Multiplicity a a Br d
One gram of ampicillin (C16H19N3O4S) MW 349 , was dissolved in 180 mL of water. Using 2 dm tube, this solution was found out to have an angular rotation of +2.83° and that of the solvent is +3.5°. Calculate the molar rotation.
Under C4v symmetry, which irreducible representations, if any, correspond to an IR active vibration and which ones correspond to a Raman active vibration? And which ones correspond to an IR active vibration under D2h symmetry?
Preview File Edit View Go Tools Window Help 62% Thu 1:13 PM S HomeworkSet3.pat - Q Search View Znem Share Hghight Rotale Marke Sarch 3) Reduce the following representations into its corresponding reducible representations: a) Under Czv symmetry: Tr = 9 -1 1 3 b) Under Dzd symmetry: r, = 13 -1 -3 5 -1 c) Under D3h symmetry: T, = 7 1 -3 -1 -1 1 20 Imaoes M Videos O Shoopina News 1 More Tools 17 B.
The structure of [NO3]-is either trigonal planar or trigonal pyramidal draw both possible structures and determine the point group for each. Which irreducible representations represent the translational and rotational modes for each possible structure of [NO3]-? Which irreducible representations correspond to the vibrational modes for each possible structure of [NO3]-? How many degrees of freedom would you expect for each structure of [NO3]-? Calculate T-vibrationaland determine which modes you expect to be IR active for each structure.
Draw the Lewis structure of the following compounds and identify the point group. Indicate the symmetry operations you performed in determining the point groups.a. 1,8-Dichloronaphthaleneb. Eclipsed dibenzenechromium (Hint: The Cr atom is sandwiched between the two-benzene ring in eclipsed conformation.)c. Borazine (B3H6N3) (Hint: The structure looks like benzene, but instead of C, B and N are the atoms in alternating order.)
Stannous fluoride, or Tn(1l) fluoride, is a compound commonly used in toothpastes with similar in function and activity to sodium fluoride (NaF), the conventionally added ingredient in toothpastes, but has been shown to be more effective. Draw the predicted 11Sn and 1F NMR spectra of stannous fluoride. The table shows the natural abundance of the NMR active nuclei of interest with their magnetogyric ratios. NIMR active Magnetogyric tatio (10 rad/s) NA E Isotope 1155n 0.35 1/2 -8.80 117Sn 7.61 1/2 -9,59 1195n 8.58 1/2 -10.01 19F 100 1/2 25.18 Stannous Fluoride (SnF2) V =
1. Give the point group for each of the following molecules: H H H CI F F H H. CI BrH BrH Br Br Br Br CI H. Сyclohexane (chaй) Cyclohexane (boat) Ferrocene (staggard) Ferrocene (eclisped) 2. Give the point group for each of the following atomic and molecular orbitals: 88 dy d22 o bond n bond z antibond sp3