Reactions of Alkyl and Aryl halides
In organic chemistry, an alkyl halide is formed when an atom of hydrogen is switched by a halogen in a hydrocarbon or aliphatic compound. An aryl halide is formed when an atom of hydrogen is substituted by a halogen atom in an aromatic compound. Metals react with aryl halides and alkyl halides and they also go through nucleophilic substitution reactions and elimination reactions.
Zaitsev's Rule in Organic Chemistry
Alexander Zaitsev (also pronounced as Saytzeff), in 1875, prepared a rule to help predict the result of elimination reactions which stated, "The favored product in dehydrohalogenation reactions is that alkene that has the majority of alkyl groups attached to the double-bonded carbon atoms."
Tosylate
Tosylates are important functional groups in organic chemistry, mainly because of two important properties which they possess:
Alkyl Halides
A functional group is a collection of several atoms or bonds with certain characteristic chemical properties and reactions associated with it. There is a presence of a halogen atom (F, Cl, Br, or I; it represents any halogen atom), as a functional group in alkyl halides. Therefore, it can be said that alkanes that contain a halogen compound are called alkyl halides.
![**Title: Identifying the Major Product in a Multi-Step Organic Reaction**
**Question:**
Choose the correct major product for the following reaction:
**Reaction Details:**
- Starting Material: A six-membered lactam (cyclic amide) compound with an N-methyl group.
- Reaction Steps:
1. Lithium aluminum hydride (LiAlH₄) in excess (xs)
2. Water (H₂O)
3. Under acidic conditions ([H⁺]), the intermediate is reacted with acetone and sodium cyanoborohydride (NaBH₃CN).
**Potential Products:**
- **A:** A cyclic amide with an additional N-isopropyl group.
- **B:** A cyclic alcohol with a tertiary alcohol group and an N-methyl group.
- **C:** A linear compound with a 1,5-diol structure and an N-isopropyl group.
- **D:** A cyclic amine with an N-isopropyl group.
**Product Options:**
- ○ A
- ○ B
- ○ C
- ○ D
**Explanation of Reaction Steps:**
1. **Reduction with LiAlH₄:** Converts the lactam into a cyclic amine. This step involves the reduction of the carbonyl group in the lactam to an amine.
2. **Protonation with Water:** Quenches the excess hydride, providing the uncharged, reduced amine.
3. **Reductive Amination:** The amine then undergoes reductive amination with acetone under acidic conditions using NaBH₃CN, adding an isopropyl group to the nitrogen.
The task is to determine which of the given options corresponds to the description of the product after these reactions. The reaction likely produces a cyclic amine with an N-substituted isopropyl group, given the use of acetone and NaBH₃CN in reductive amination.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F56b89a6c-6ca3-4f25-9a44-1409c69966fc%2F7d7ba31b-a42a-4906-97ae-f646768b7ada%2Ftt125p_processed.png&w=3840&q=75)
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