Give each product in the series of reactions shown below CH3CI AIC3 NaNO2, HCI, 0°C CUCN E HNO3 Sn В HCI A -D H2SO4

Chemistry
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Chapter1: Chemical Foundations
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**Title: Understanding Multi-Step Organic Synthesis Reactions**

**Introduction to Reaction Pathway:**

This sequence illustrates a series of chemical reactions starting from benzene and culminating in the formation of a final product, labeled as compound F. Each step in the reaction pathway transforms the initial substrate into various intermediates (A-F) via specific reagents and conditions.

**Reaction Pathway:**

1. **Starting Material:**
   - **Benzene** (Aromatic compound with alternating double bonds)

2. **First Reaction:**
   - **Reagents:** CH₃Cl and AlCl₃
   - **Reaction Type:** Friedel-Crafts Alkylation
   - **Product:** Compound A (Methylbenzene or Toluene)

3. **Second Reaction:**
   - **Reagents:** HNO₃ and H₂SO₄
   - **Reaction Type:** Nitration 
   - **Product:** Compound B (Nitrotoluene)

4. **Third Reaction:**
   - **Reagents:** Sn and HCl
   - **Reaction Type:** Reduction
   - **Product:** Compound C (Aminotoluene or Toluidine)

5. **Fourth Reaction:**
   - **Reagent/Condition:** OH⁻ (Base)
   - **Reaction Type:** Diazotization following reduction
   - **Product:** Compound D (Diazotized intermediate)

6. **Fifth Reaction:**
   - **Reagents/Conditions:** NaNO₂, HCl at 0°C
   - **Reaction Type:** Diazotization
   - **Product:** Compound E (Diazonium salt)

7. **Final Reaction:**
   - **Reagent:** CuCN
   - **Reaction Type:** Sandmeyer Reaction
   - **Product:** Compound F (Benzonitrile derivative)

**Conclusion:**

This reaction series demonstrates key transformations in organic chemistry, including electrophilic aromatic substitution, reduction, diazotization, and Sandmeyer reactions. Understanding each step's conditions and products is essential for synthesizing desired compounds efficiently.
Transcribed Image Text:**Title: Understanding Multi-Step Organic Synthesis Reactions** **Introduction to Reaction Pathway:** This sequence illustrates a series of chemical reactions starting from benzene and culminating in the formation of a final product, labeled as compound F. Each step in the reaction pathway transforms the initial substrate into various intermediates (A-F) via specific reagents and conditions. **Reaction Pathway:** 1. **Starting Material:** - **Benzene** (Aromatic compound with alternating double bonds) 2. **First Reaction:** - **Reagents:** CH₃Cl and AlCl₃ - **Reaction Type:** Friedel-Crafts Alkylation - **Product:** Compound A (Methylbenzene or Toluene) 3. **Second Reaction:** - **Reagents:** HNO₃ and H₂SO₄ - **Reaction Type:** Nitration - **Product:** Compound B (Nitrotoluene) 4. **Third Reaction:** - **Reagents:** Sn and HCl - **Reaction Type:** Reduction - **Product:** Compound C (Aminotoluene or Toluidine) 5. **Fourth Reaction:** - **Reagent/Condition:** OH⁻ (Base) - **Reaction Type:** Diazotization following reduction - **Product:** Compound D (Diazotized intermediate) 6. **Fifth Reaction:** - **Reagents/Conditions:** NaNO₂, HCl at 0°C - **Reaction Type:** Diazotization - **Product:** Compound E (Diazonium salt) 7. **Final Reaction:** - **Reagent:** CuCN - **Reaction Type:** Sandmeyer Reaction - **Product:** Compound F (Benzonitrile derivative) **Conclusion:** This reaction series demonstrates key transformations in organic chemistry, including electrophilic aromatic substitution, reduction, diazotization, and Sandmeyer reactions. Understanding each step's conditions and products is essential for synthesizing desired compounds efficiently.
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