Calculate the estimated concentration of test agent that inhibit cell growth by 50% ( GI50) value

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Calculate the estimated concentration of test agent that inhibit cell growth by 50% ( GI50) value
Paste
BIU
E E EE
.00 20
Undo
Clipboard
Font
Alignment
Numbe
fx
A
Temazolomide
Standard deviation
TO
a
Concentration um absorbance
B control
1.606
0.2325
0.12
1.2655
0.0998
0.12
4.
10
0.8017
0.3251
0.12
50
0.72
0.129167
0.12
100
0.62
0.0603
0.12
7.
500
8.
9.
10
11
12
1.8
13
1.6
14
1.4
15
1.2
16
17
18
0.8
0.6
19
20
0.4
21
0.2
22
23
Sheet1
Sheet2
Ready
* Accessibility: Investigate
7°C
Clear
Absorbance (450nm)
ili
Transcribed Image Text:Paste BIU E E EE .00 20 Undo Clipboard Font Alignment Numbe fx A Temazolomide Standard deviation TO a Concentration um absorbance B control 1.606 0.2325 0.12 1.2655 0.0998 0.12 4. 10 0.8017 0.3251 0.12 50 0.72 0.129167 0.12 100 0.62 0.0603 0.12 7. 500 8. 9. 10 11 12 1.8 13 1.6 14 1.4 15 1.2 16 17 18 0.8 0.6 19 20 0.4 21 0.2 22 23 Sheet1 Sheet2 Ready * Accessibility: Investigate 7°C Clear Absorbance (450nm) ili
2
1.8
1.6
1.4
1.2
1
0.8
0.6
0.4
0.2
control
10
50
100
500
Concentration
absorbance
-TO
Figure 1. Graph showinf Growth inhibitory effects of Temazolomide on HCT-116
cells. absorbance Cells were seeded at a density of 2.5 x 10^3 cells/well in 96-well
plates and incubated for 72 h
Absorbance (450nm)
Transcribed Image Text:2 1.8 1.6 1.4 1.2 1 0.8 0.6 0.4 0.2 control 10 50 100 500 Concentration absorbance -TO Figure 1. Graph showinf Growth inhibitory effects of Temazolomide on HCT-116 cells. absorbance Cells were seeded at a density of 2.5 x 10^3 cells/well in 96-well plates and incubated for 72 h Absorbance (450nm)
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