Blood sugar homeostasis: Indicate the order of events that will happen following blood glucose increase after a meal.Increased blood glucose1234LO56::::Glucose transport via GLUT4Glucose transport into pancreatic cellsInsulin binds to insulin receptorInsulin release from pancreatic beta-cellsSecond messenger signaling pathway is activatedGLUT4 moves to plasma membraneDecreased blood glucose AND muscle makes ATP and glycogen

After a meal, blood glucose increases. To maintain blood glucose level, insulin is released by the…

Answered: Blood sugar homeostasis: Indicate the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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an individual with high plasma insulin along with hyperglycemia is potentially what? Type two diabetic, type one diabetic, or type two pre-diabetic
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In order for a fatty acid stored in an adipocyte to be oxidized by a muscle cell, which of the following will need to be present/utilized? Check all that apply. Multiple answers can be selected Acyl CoA Synthetase CD36 malate-aspartate shuttle dephosphorylated hormone-sensitive lipase GLUT 4
In 3-4 sentences, briefly explain how lactate is formed, the biological effect of lactate, and explain the biochemical process and path for conversion of lactate. 3. The hormones glucagon, epinephrine, and insulin, can regulate blood glucose levels to protect the brain. For each one provide a short explanation as to whether it raises or lowers glucose how it does this, and indicate whether it is metabolic or catabolic.
29)
Activation of cAMP phosphodiesterase _________________________. Stimulates the phosphorylation of glycogen synthase Stimulates the phosphorylation of phosphorylase kinase Stimulates the phosphorylation of PFK-2 Stimulates the phosphorylation of glycogen synthase kinase 3 All of the above None of the above Which of the following is likely to occur in type I diabetic patients? A decreased level of agouti-related peptide (AgRP) A decreased level of melanocortin Both A and B Neither A nor B
what is the effects of muscle glycogen phosphorylase deficiency. abnormally high levels of skeletal muscle glycogen. skeletal muscle glycogen with an abnormally high degree of branching. a deficiency of skeletal muscle glycogen. decreased production of lactate under conditions of strenuous activity. an inability to import glucose into the cell.
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In the indicated tissues, how will each process or the activity of each enzyme below be affected by the signal sent upon Glucagon secretion? Use an up (t) or down (1) arrow or NC (no change). (Hint: Decide what pathways will be up-regulated first, then look at the enzymes below!) + Triacylglygerol Lipase (Adipocytes) Phosphofructokinase-2 (Liver) Insulin secretion (Pancreas) Pyruvate Kinase (Muscle) Glycogen Phosphorylase (Liver) Phosphofructokinase-1 (Liver) Fructose-1,6-bisphosphatase 1 (Liver) Fatty Acid Biosynthesis (Liver) PEP Carboxxkinase (Liver) Phosphorylation of Perilipins (Adipocytes) Adenylate Cyclase (Liver) Glycogen Synthase (Liver) Acetyl CoA Carboxylase Hexokinase II (Muscle)
Many signals. Match the characteristic (a-i) with the appropriate hormone (1-6). de a. Secreted by adipose tissue. 1. leptin b. Stimulates liver gluconeogenesis. 2. adiponectin c. GPCR pathway d. Satiety signal. 3. GLP-1 4. CCK e. Enhances insulin secretion 5. insulin f. Secreted by the pancreas during a fast 6. glucagon g. Secreted after a meal. h. Stimulates glycogen synthesis i. Missing in type 1 diabetes
Consider regulation of glycolysis vs gluconeogenesis in the liver. Which of the following are more likely to promote the activity of gluconeogenesis rather than glycolysis? (select all that apply) Group of answer choices An increase in the ATP/AMP ratio A decrease/lack of F-2,6-BP The cell is in a low energy state Insulin signaling Glucagon signaling An abundance of citric acid cycle intermediates (i.e. citrate) Intense exercise Inhibition of pyruvate carboxylase Fasting
Which of these enzymes/complexes will insulin activate in the liver? Choose all that apply. Glycogen synthase Glycogen phosphorylase Acetyl-CoA carboxylase Carnitine shuttle PFK-1 FBPase-1

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