Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
Question 8: The following table shows the glycolysis reactions and their standard Gibbs free energy changes at 25 C. Answer the following questions: A. What is the Gibbs free energy expression of the glycolysis pathway? B. What is the overall reaction of the glycolysis pathway? C. Suppose that the physiological concentrations of some metabolites are known as follows: micromolar Pyruvate 380 NADH 50 H* 0.1 ATP ? Glucose 3000 NAD+ 540 ADP ? Pi 3500 What should be the ATP:ADP ratio so that the glycolysis proceeds spontaneously at 25 C? The Reactions of Glycolysis and Their Standard Free-Energy Changes Step Enzyme AG kJ mol kcal mol Reaction Glucose + ATP → Glucose-6-phosphate + ADP Hexokinase/ Glucokinase -16.7 -4.0 Glucose-6-phosphate →Fructose-6-phosphate Fructose-6-phosphate + ATP → Fructose-l, 6-bisphosphate + ADP Fructose-1,6-bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 2 Glucose phosphate isomerase +1.67 +0.4 3 Phosphofructokinase -14.2 -3.4 Aldolase +23.9 +5.7 Dihydroxyacetone phosphate→ Glyceraldehyde- 3-phosphate Triose phosphate isomerase +7.56 +1.8 2(Glyceraldehyde-3-phosphate + NAD* + P, → 1,3-bisphosphoglycerate + NADH + H") Glyceraldehyde-3-P dehydrogenase 2(+6.20) 2(+1.5) 7 Phosphoglycerate kinase 2(1,3-bisphosphoglycerate + ADP → 3-Phosphoglycerate + ATP) 2(-18.8) 2(-4.5) 2(3-Phosphoglycerate →2-Phosphoglycerate) Phosphoglyceromutase 2(+4.4) 2(+1.1) 9. 2(2-Phosphoglycerate - Phosphoenolpyruvate + H,O) Enolase 2(+1.8) 2(+0.4) 2(Phosphoenolpyruvate + ADP → Pyruvate + ATP) 10 Pyruvate kinase 2(-31.4) 2(-7.5)

Question 8: The following table shows the glycolysis reactions and their standard Gibbs free energy changes at 25 C. Answer the following questions: A. What is the Gibbs free energy expression of the glycolysis pathway? B. What is the overall reaction of the glycolysis pathway? C. Suppose that the physiological concentrations of some metabolites are known as follows: micromolar Pyruvate 380 NADH 50 H* 0.1 ATP ? Glucose 3000 NAD+ 540 ADP ? Pi 3500 What should be the ATP:ADP ratio so that the glycolysis proceeds spontaneously at 25 C? The Reactions of Glycolysis and Their Standard Free-Energy Changes Step Enzyme AG kJ mol kcal mol Reaction Glucose + ATP → Glucose-6-phosphate + ADP Hexokinase/ Glucokinase -16.7 -4.0 Glucose-6-phosphate →Fructose-6-phosphate Fructose-6-phosphate + ATP → Fructose-l, 6-bisphosphate + ADP Fructose-1,6-bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 2 Glucose phosphate isomerase +1.67 +0.4 3 Phosphofructokinase -14.2 -3.4 Aldolase +23.9 +5.7 Dihydroxyacetone phosphate→ Glyceraldehyde- 3-phosphate Triose phosphate isomerase +7.56 +1.8 2(Glyceraldehyde-3-phosphate + NAD* + P, → 1,3-bisphosphoglycerate + NADH + H") Glyceraldehyde-3-P dehydrogenase 2(+6.20) 2(+1.5) 7 Phosphoglycerate kinase 2(1,3-bisphosphoglycerate + ADP → 3-Phosphoglycerate + ATP) 2(-18.8) 2(-4.5) 2(3-Phosphoglycerate →2-Phosphoglycerate) Phosphoglyceromutase 2(+4.4) 2(+1.1) 9. 2(2-Phosphoglycerate - Phosphoenolpyruvate + H,O) Enolase 2(+1.8) 2(+0.4) 2(Phosphoenolpyruvate + ADP → Pyruvate + ATP) 10 Pyruvate kinase 2(-31.4) 2(-7.5)

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question

please show steps. Please be clear as possible. Thank you !!!

Question 8: The following table shows the glycolysis reactions and their standard Gibbs free energy changes at 25 C. Answer the following questions: A. What is the Gibbs free energy expression of the glycolysis pathway? B. What is the overall reaction of the glycolysis pathway? C. Suppose that the physiological concentrations of some metabolites are known as follows:
Transcribed Image Text:Question 8: The following table shows the glycolysis reactions and their standard Gibbs free energy changes at 25 C. Answer the following questions: A. What is the Gibbs free energy expression of the glycolysis pathway? B. What is the overall reaction of the glycolysis pathway? C. Suppose that the physiological concentrations of some metabolites are known as follows:
micromolar Pyruvate 380 NADH 50 H* 0.1 ATP ? Glucose 3000 NAD+ 540 ADP ? Pi 3500 What should be the ATP:ADP ratio so that the glycolysis proceeds spontaneously at 25 C? The Reactions of Glycolysis and Their Standard Free-Energy Changes Step Enzyme AG kJ mol kcal mol Reaction Glucose + ATP → Glucose-6-phosphate + ADP Hexokinase/ Glucokinase -16.7 -4.0 Glucose-6-phosphate →Fructose-6-phosphate Fructose-6-phosphate + ATP → Fructose-l, 6-bisphosphate + ADP Fructose-1,6-bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 2 Glucose phosphate isomerase +1.67 +0.4 3 Phosphofructokinase -14.2 -3.4 Aldolase +23.9 +5.7 Dihydroxyacetone phosphate→ Glyceraldehyde- 3-phosphate Triose phosphate isomerase +7.56 +1.8 2(Glyceraldehyde-3-phosphate + NAD* + P, → 1,3-bisphosphoglycerate + NADH + H") Glyceraldehyde-3-P dehydrogenase 2(+6.20) 2(+1.5) 7 Phosphoglycerate kinase 2(1,3-bisphosphoglycerate + ADP → 3-Phosphoglycerate + ATP) 2(-18.8) 2(-4.5) 2(3-Phosphoglycerate →2-Phosphoglycerate) Phosphoglyceromutase 2(+4.4) 2(+1.1) 9. 2(2-Phosphoglycerate - Phosphoenolpyruvate + H,O) Enolase 2(+1.8) 2(+0.4) 2(Phosphoenolpyruvate + ADP → Pyruvate + ATP) 10 Pyruvate kinase 2(-31.4) 2(-7.5)
Transcribed Image Text:micromolar Pyruvate 380 NADH 50 H* 0.1 ATP ? Glucose 3000 NAD+ 540 ADP ? Pi 3500 What should be the ATP:ADP ratio so that the glycolysis proceeds spontaneously at 25 C? The Reactions of Glycolysis and Their Standard Free-Energy Changes Step Enzyme AG kJ mol kcal mol Reaction Glucose + ATP → Glucose-6-phosphate + ADP Hexokinase/ Glucokinase -16.7 -4.0 Glucose-6-phosphate →Fructose-6-phosphate Fructose-6-phosphate + ATP → Fructose-l, 6-bisphosphate + ADP Fructose-1,6-bisphosphate Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate 2 Glucose phosphate isomerase +1.67 +0.4 3 Phosphofructokinase -14.2 -3.4 Aldolase +23.9 +5.7 Dihydroxyacetone phosphate→ Glyceraldehyde- 3-phosphate Triose phosphate isomerase +7.56 +1.8 2(Glyceraldehyde-3-phosphate + NAD* + P, → 1,3-bisphosphoglycerate + NADH + H") Glyceraldehyde-3-P dehydrogenase 2(+6.20) 2(+1.5) 7 Phosphoglycerate kinase 2(1,3-bisphosphoglycerate + ADP → 3-Phosphoglycerate + ATP) 2(-18.8) 2(-4.5) 2(3-Phosphoglycerate →2-Phosphoglycerate) Phosphoglyceromutase 2(+4.4) 2(+1.1) 9. 2(2-Phosphoglycerate - Phosphoenolpyruvate + H,O) Enolase 2(+1.8) 2(+0.4) 2(Phosphoenolpyruvate + ADP → Pyruvate + ATP) 10 Pyruvate kinase 2(-31.4) 2(-7.5)
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS