F.28. How will phosphorylation of serine change the pKa of Arg, increase, decrease, or no change
F.28. How will phosphorylation of serine change the pKa of Arg, increase, decrease, or no change
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
F.28.
How will phosphorylation of serine change the pKa of Arg, increase, decrease, or no change
Expert Solution
Step 1
Serine is a polar but uncharged residue. Arginine is a basic residue due to the presence of an amine group in its side chain. Proteins are phosphorylated at serine, threonine, and tyrosine residues. Phosphorylation generally occurs on the side chains having hydroxylic groups.
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