B cells express a complement receptor that binds to C3b cleavage products, such as iC3b and C3dg. When a B cell with an antigen receptor that specifically recognizes that pathogen also has its complement receptor stimulated because the pathogen is opsonized with these C3 fragments,

Q: According to the clonal selection theory, all immunoglobulin molecules in an individual B cell have…

A: *clonal selection theory states that antigen selects lymphocytes for activation from some cells  to…

Q: Type I interferons help fight against intracellular infection. Explain how it functions, what type…

A: The diseases that can be spread via air, water, or any other medium from an infected to a healthy…

Q: Explain the typical immunophenotypic features of peripheral B cells in: (i) X-linked…

A:

Q: Pathogens produce several types of proteins that can inhibit complement activation. The importance…

A: Complement activation is one of the most important ways of innate immune system, to get rid of…

Q: The following events occur in humoral immunity, leading to an activated B cell in a T dependent…

A: Humoral immunity is a crucial component of the immune system that involves the production of…

Q: Describe briefly the three effector functions of complement activation that result from the initial…

A:

Q: Which of the following statements is NOT correct? Group of answer choices -Natural killer cells are…

A: In both human and mice NK cells are known for directly inducing the death of tumor cells. They act…

Q: What accounts for the change in a B cell’s ability to bind antigen?

A: B cells are also known as B lymphocytes are special types of blood cells which belong to the group…

Q: Describe the interaction between a dendritic cell and a helper T cell that can recognize an Ebola…

A: Antigens are foreign elements that stimulate the production of antibodies by activation of the…

Q: A patient has contracted an upper respiratory infection caused by a virus. Her initial adaptive…

A: Immunity is the body’s ability to resist and eliminate the potential harmful foreign invaders to…

Q: A mouse is infected with staphylococcal bacteria through a laceration in the skin of its paw.…

A: Dendritic cells are important immune system regulators. They act as a bridge between the innate and…

Q: y knocking out the following enes: ion of classical pathway C3 convertase ion of alternative pathway…

A: complement system refers to a series of more than 20 proteins circulating in blood and tissue…

Q: Which of the following types of antibodies may function to trigger the nonspecific event of…

A: Antibody or immunoglobulins (Ig) are circulating glycoprotein molecules, secreted by B-lymphocyte…

Q: Explain why an inherited deficiency in complement components C3 or C4 can result in less efficient…

A: Complement component 3 deficiency is a rare genetic primary immunodeficiency characterised by…

Q: Put the following steps in order for cell-mediated immunereactions:(a) Differentiated T cells…

A: Cell-mediated immune response can be defined as the immune response generated by the cells such as…

Q: If a B cell receptor does not pass selection, is it better to be self-reactive against a…

A: In the primary lymphoid organs, such as lymph nodes and spleen, the selection is positive and…

Q: What is the activation signal for NK cells? How doesthis differ from the activity of T-cytotoxic…

A: Introduction: Natural killer cells are lymphocytes of the same family as T and B cells. They are…

Q: Explain the mechanism by which NK cells are able to engage a highly specific antigen receptor during…

A: NK cells are produced from red bone marrow. They typically kill virus-infected cells and cancerous…

Q: Which of the following statements is TRUE about NK cells? Select an answer and submit. For keyboard…

A: Natural Killer (NK) cells are a type of cytotoxic immune cell that play a role in the rejection of…

Q: rue/False: Several pathogens produce proteins, either membrane-bound or secreted, that inactivate…

A: The organisms that cause the disease to any human is known as the pathogen. The organism a…

Q: Cancer cells often underexpress MHC class 1 molecules. Due to these characteristics, they may be the…

A: MHC class I molecules are heterodimers containing a heavy chain of about 350 amino acids and a light…

Q: Patients with DiGeorge syndrome may fail to produce IgG in response to immunization with T-dependent…

A: Introduction:- DiGeorge Syndrome is a primary immunodeficiency disorder characterised by aberrant…

Q: Which of the following is true about complement? Check all that apply. Three pathways of…

A:

Q: What immune defense would be most impacted for a patient with a C9 complement protein deficiency? Be…

A: The complement system is a complex network of proteins that play a vital role in the immune…

Q: B-cell tumors originate during different developmental stages of B cells during their maturation in…

A: B cells are also termed B lymphocytes, they are known as white blood cells of the lymphocyte…

Q: It has been suggested that complexes of IgE with allergen can be transferred from mother to child…

A: An Allergic infant will normally have symptoms in several body systems. An increased immunoglobulin…

Q: The mechanism of cross-presentation by dendritic cells is an essential pathway for generating CD8 T…

A: Cross-presentation is the capacity of specific skilled antigen-presenting cellscells to adopt,…

Q: Immature B cells arriving in the spleen turn over rapidly and require cytokines and positive signals…

A: Immature B cells are progenitors to B cells, which play an important role in preventing…

Q: Which of the following proteins downregulates the classical complement cascade by breaking up the C3…

A: The classical complement (CMP) pathway is considered as the method, which helps in the activation of…

Q: Explain the typical immunophenotypic features of peripheral B cells in: (i) X-linked…

A: X-linked agammaglobulinemia  also called XLA - is an inherited (genetic) immune system disorder that…

Q: The formation of the C3 convertase is a key step in complement activation that occurs in all three…

A: The complementary system occurs in the cascade of reactions which is a part of the immune system. It…

Q: During the early developmental stages of α:β T cells in the thymus, there are two key checkpoints…

A: The T cells are mainly derived from hematopoietic stem cells present in the bone marrow. The…

Q: Individuals infected with herpes simplex virus (HSV) mount protective antibody responses directed…

A: The complement system of our innate immunity depends on the protein C3. C3 is another name for the…

Q: The PAMP recognized by TLR3 is doublestranded RNA (dsRNA). Against which pathogens would TLR3 be an…

A: Antigens are substances that activate the immune system of the body. Antibodies are antigen-binding…

Q: Describe how helper T cells stimulate an increase in thenumber of B cells or T cells. Why is this…

A: Helper T cells are very important for the adaptive immunity. They are required for the activation of…

Q: Inhibitory receptors on lymphocytes down-regulate immune responses by recruiting protein or lipid…

A: B cells, also known as B lymphocytes, are part of adaptive immunity, which is antigen-specific and…

Q: Phagocytes bind to pathogen-associated molecular patterns (PAMPS) via: complement O antimicrobial…

A: Introduction :- Immune system consists of immune cells , their Secretion , to fight the foreign…

Q: The diagram shows a pathogen (in red) that is present in different cellular compartments of each of…

A: Immunity refers to the body's ability to protect itself against disease-causing germs. Nearly every…

Q: PAMPS, TLRs, interferon

A: Human immunodeficiency virus (HIV) is a virus which attacks the human (body's) immune system.   it…

Q: The B-cell co-receptor, composed of CD19/CD21/CD81, is a receptor that binds to complement fragments…

A: A co-receptor is a type of cell surface receptor that functions by binding a signaling molecule in…

Q: Name two cytokines that are thought to be involved in the inflammatory response to viruses (cite…

A: We are answering first question only and not mentioning the cite source as we can answer the…

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.