As you increase the number of alanine residues in the oligopeptide chain:The pKas of the carboxylate groups will [increase, decrease, stay the same]The pKas of the amino groups will [increase, decrease, stay the same] Given below are structures of alanine and some alanine oligomers,H,N-CH- COOCH,H,N-CH-c-NH-CH-cooCH,CH,CH,H,N-CH-C-NH-CH-C-C-NH-CH-cooCH,H,N-O-c-NH-O-c-N-O-ç-NH--cooEach of the charged groups in each of the structures have a pka value. What do you think will be the trend of the pK,s as you increase the number of alanine residues in theoligopeptide chain (that is, as you go from the monomeric alanine towards the longest alanine oligomer)?As you increase the number of alanine residues in the oligopeptide chain:

The amino acids which contain ionizable side chain groups can participate in an acid-base…

As you increase the number of alanine residues in the oligopeptide chain: The pKas of the carboxylate groups will [increase, decrease, stay the same] The pKas of the amino groups will [increase, decrease, stay the same]

As you increase the number of alanine residues in the oligopeptide chain: The pKas of the carboxylate groups will [increase, decrease, stay the same] The pKas of the amino groups will [increase, decrease, stay the same]

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

As you increase the number of alanine residues in the oligopeptide chain:

The pK_as of the carboxylate groups will [increase, decrease, stay the same]
The pK_as of the amino groups will [increase, decrease, stay the same]

Given below are structures of alanine and some alanine oligomers,
H,N-CH- COO
CH,
H,N-CH-c-NH-CH-coo
CH,
CH,
CH,
H,N-CH-C-NH-CH-C
-C-NH-CH-coo
CH,
H,N-O-c-NH-O-c-N-O-ç-NH--coo
Each of the charged groups in each of the structures have a pka value. What do you think will be the trend of the pK,s as you increase the number of alanine residues in the
oligopeptide chain (that is, as you go from the monomeric alanine towards the longest alanine oligomer)?
As you increase the number of alanine residues in the oligopeptide chain:

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