In humans, there are four typical modes of inheritance for Mendelian diseases: autosomal recessive, autosomal dominant, X-linked recessive, and X-linked dominant. For any pedigree, we may or may not be able to exclude some of these possibilities. Assume that no new mutations arise within the pedigrees-the disease-causing alleles are present from the start. a b c

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
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Chapter1: The Human Body: An Orientation
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a) Which of the four modes of inheritance are consistent with the disease shown in this human pedigrees below? (List the compatible mode or modes) Give an answer for a, b and c

b) If the parents in pedigree c have 2 other children, what is the probability that they will carry the disease?

In humans, there are four typical modes of inheritance for Mendelian diseases: autosomal
recessive, autosomal dominant, X-linked recessive, and X-linked dominant. For any pedigree, we
may or may not be able to exclude some of these possibilities. Assume that no new mutations arise
within the pedigrees-the disease-causing alleles are present from the start.
a
b
с
Transcribed Image Text:In humans, there are four typical modes of inheritance for Mendelian diseases: autosomal recessive, autosomal dominant, X-linked recessive, and X-linked dominant. For any pedigree, we may or may not be able to exclude some of these possibilities. Assume that no new mutations arise within the pedigrees-the disease-causing alleles are present from the start. a b с
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Are any of them X-linked recessive or X-linked dominant?

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