Answer the following questions for the reaction scheme below: OH e :CEN 1 + H-CEN phenol cyanide phenolate hydrogen cyanide pka = 10.0 pka = 3.46 a. The equilibrium favors the [Select] V b. This reaction is best described as a(n) [Select] c. The strongest acid in the reaction is the [Select] d. The nucleophile in the forward reaction is [Select] e. The electrophile in the reverse reaction is [Select] + V reaction.

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### Reaction Scheme Analysis

**Answer the following questions for the reaction scheme below:**

**Reaction Scheme:**
- **Reactants:** Phenol (pKa = 10.0) and Cyanide
- **Products:** Phenolate and Hydrogen Cyanide (pKa = 3.46)

\[ \text{Phenol} + \text{Cyanide} \leftrightharpoons \text{Phenolate} + \text{Hydrogen Cyanide} \]

---

#### Questions:

a. The equilibrium favors the [ Select ].

b. This reaction is best described as a(n) [ Select ] reaction.

c. The strongest acid in the reaction is the [ Select ].

d. The nucleophile in the forward reaction is [ Select ].

e. The electrophile in the reverse reaction is [ Select ].

---

**Note:**
In the reaction scheme:
- The molecular structures for each compound (phenol, cyanide, phenolate, and hydrogen cyanide) are displayed.
- The pKa values of phenol (10.0) and hydrogen cyanide (3.46) are given, which are crucial for determining the direction of the equilibrium and the relative strengths of the acids and bases.

**Detailed Explanation of Terms:**
- **Equilibrium:** The point at which the concentrations of reactants and products remain constant over time.
- **Acid-Base Reaction:** A chemical reaction that involves the transfer of protons (H⁺ ions) between reactants.
- **Strongest Acid:** The acid with the lowest pKa value.
- **Nucleophile:** A species that donates an electron pair to form a chemical bond in reaction.
- **Electrophile:** A species that accepts an electron pair to form a chemical bond in reaction.

To solidify your understanding, utilize this information to select the correct options when analyzing acid-base equilibria and reaction mechanisms.

---
Transcribed Image Text:--- ### Reaction Scheme Analysis **Answer the following questions for the reaction scheme below:** **Reaction Scheme:** - **Reactants:** Phenol (pKa = 10.0) and Cyanide - **Products:** Phenolate and Hydrogen Cyanide (pKa = 3.46) \[ \text{Phenol} + \text{Cyanide} \leftrightharpoons \text{Phenolate} + \text{Hydrogen Cyanide} \] --- #### Questions: a. The equilibrium favors the [ Select ]. b. This reaction is best described as a(n) [ Select ] reaction. c. The strongest acid in the reaction is the [ Select ]. d. The nucleophile in the forward reaction is [ Select ]. e. The electrophile in the reverse reaction is [ Select ]. --- **Note:** In the reaction scheme: - The molecular structures for each compound (phenol, cyanide, phenolate, and hydrogen cyanide) are displayed. - The pKa values of phenol (10.0) and hydrogen cyanide (3.46) are given, which are crucial for determining the direction of the equilibrium and the relative strengths of the acids and bases. **Detailed Explanation of Terms:** - **Equilibrium:** The point at which the concentrations of reactants and products remain constant over time. - **Acid-Base Reaction:** A chemical reaction that involves the transfer of protons (H⁺ ions) between reactants. - **Strongest Acid:** The acid with the lowest pKa value. - **Nucleophile:** A species that donates an electron pair to form a chemical bond in reaction. - **Electrophile:** A species that accepts an electron pair to form a chemical bond in reaction. To solidify your understanding, utilize this information to select the correct options when analyzing acid-base equilibria and reaction mechanisms. ---
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