Anisole undergoes demethylation to phenol by CYP450. Draw the full mechanism for the demethylation showing any intermediates that are formed in the reaction. The involvement of Fe should be shown, however, the haem structure and oxidation cycle for Fe in the CYP450 enzyme is is not required in this answer.
Anisole undergoes demethylation to phenol by CYP450. Draw the full mechanism for the demethylation showing any intermediates that are formed in the reaction. The involvement of Fe should be shown, however, the haem structure and oxidation cycle for Fe in the CYP450 enzyme is is not required in this answer.
Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter14: Chemical Kinetics: The Rates Of Chemical Reactions
Section14.7: Reaction Mechanisms
Problem 1.1ACP
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