Compartmentation in ß oxidation. Free palmitate is activated to its coenzyme A derivative (palmitoyl-CoA) in the cytosol before it can be oxidized in the mitochondrion. If palmitate and radioactive [14C]coenzyme A are added to hepatocytes, palmitoyl-CoA isolated from the cytosolic fraction is radioactive, but that isolated from mitochondrial fraction is not. Explain
Compartmentation in ß oxidation. Free palmitate is activated to its coenzyme A derivative (palmitoyl-CoA) in the cytosol before it can be oxidized in the mitochondrion. If palmitate and radioactive [14C]coenzyme A are added to hepatocytes, palmitoyl-CoA isolated from the cytosolic fraction is radioactive, but that isolated from mitochondrial fraction is not. Explain
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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![Compartmentation in ß oxidation. Free palmitate is activated to its coenzyme A derivative
(palmitoyl-CoA) in the cytosol before it can be oxidized in the mitochondrion. If palmitate and
radioactive [14C]coenzyme A are added to hepatocytes, palmitoyl-CoA isolated from the
cytosolic fraction is radioactive, but that isolated from mitochondrial fraction is not. Explain](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6b001819-de3d-4388-86e7-a1998bce75dd%2F2bd0055b-0bbb-4c44-829d-a44b5447f237%2Fci43mt_processed.png&w=3840&q=75)
Transcribed Image Text:Compartmentation in ß oxidation. Free palmitate is activated to its coenzyme A derivative
(palmitoyl-CoA) in the cytosol before it can be oxidized in the mitochondrion. If palmitate and
radioactive [14C]coenzyme A are added to hepatocytes, palmitoyl-CoA isolated from the
cytosolic fraction is radioactive, but that isolated from mitochondrial fraction is not. Explain
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